Multivariate survival analysis of children with medulloblastoma - A single-center experience
Journal
Pediatric Hematology and Oncology
Journal Volume
25
Journal Issue
7
Pages
647-654
Date Issued
2008
Author(s)
Abstract
The authors sought to evaluate the treatment outcome of children with medulloblastoma at a single institution. Forty-two children were analyzed. Eighty-six percent of the children who received chemotherapy were treated with cisplatin-based chemotherapy. No factors were found to affect outcome significantly. Compared with children treated before 1994 at the same institution, the median survival time was significantly longer (40 vs. 25 months, p =.0003). The authors conclude that some improvement of treatment outcome for children with medulloblastoma seemed to be achieved. Copyright ? Informa Healthcare USA, Inc.
Subjects
Children; Medulloblastoma; Outcome; Survival; Treatment
SDGs
Other Subjects
cisplatin; etoposide; adolescent; article; cancer radiotherapy; cancer surgery; cancer survival; child; clinical article; clinical protocol; disease free survival; drug dose escalation; female; human; infant; male; medulloblastoma; multiple cycle treatment; multivariate analysis; outcome assessment; overall survival; retrospective study; survival time; therapy effect; treatment outcome; treatment response; Adolescent; Antineoplastic Agents, Phytogenic; Cerebellar Neoplasms; Child; Child, Preschool; Cisplatin; Etoposide; Female; Humans; Infant; Male; Medulloblastoma; Multivariate Analysis; Radiation-Sensitizing Agents; Survival Analysis
Type
journal article