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  1. NTU Scholars
  2. 醫學院
  3. 醫學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/344018
Title: Clinical measures of physical fitness predict insulin resistance in people at risk for diabetes
Authors: Chen, CN
Chen, Mei-Ching
LEE-MING CHUANG
Chuang, LM
Wu, YT.
CHEN, CHIAO-NAN
CHUANG, LEE-MING
WU, YING-TAI
Issue Date: 2008
Journal Volume: 88
Journal Issue: 11
Start page/Pages: 1355-1364
Source: Physical Therapy 
Abstract: 
Background and Purpose. Physical inactivity has been well documented as a risk factor for type 2 diabetes. Previous studies measured the level of physical activity either with questionnaires or with direct measurements of maximum oxygen uptake. However, questionnaires are patient-report measures, and methods for obtaining direct maximum oxygen uptake measurements often are not available clinically. The purpose of this study was to investigate whether clinical measurement of health-related physical fitness with a simple test battery can predict insulin resistance, a precursor of type 2 diabetes, in people at risk for diabetes. Subjects and Methods. A total of 151 volunteers with at least one diabetes risk factor (overweight, hypertension, dyslipidemia, family history, impaired glucose tolerance, gestational diabetes, or delivering a baby weighing more than 4.0 kg) were recruited. Insulin resistance (as determined with the homeostasis model assessment of insulin resistance [HOMA-IR]), physical fitness (including body composition, as determined with the body mass index and waist circumference), muscle strength (handgrip strength [force-generating capacity]), muscle endurance (sit-up test), flexibility (sit-and-reach test), and cardiorespiratory endurance (step test) were measured, and a physical activity questionnaire was administered. Backward regression analysis was used to build the prediction models for insulin resistance from components of physical fitness and physical activity. Results. Body mass index, muscle strength, and cardiorespiratory fitness predicted HOMA-IR in men (adjusted R 2=.264). In women, age, waist circumference, and cardiorespiratory fitness were the predictors of HOMA-IR (adjusted R2=.438). Discussion and Conclusion. Clinical measures of physical fitness can predict insulin resistance in people at risk for diabetes. The findings support the validity of clinical measures of physical fitness for predicting insulin resistance in people at risk for diabetes. ? 2008 American Physical Therapy Association.
URI: http://www.scopus.com/inward/record.url?eid=2-s2.0-55849097721&partnerID=MN8TOARS
http://scholars.lib.ntu.edu.tw/handle/123456789/344018
DOI: 10.2522/ptj.20080064
metadata.dc.subject.other: article; body composition; body mass; diabetes mellitus; dyslipidemia; female; fitness; homeostasis; human; hypertension; impaired glucose tolerance; insulin resistance; major clinical study; male; muscle exercise; muscle strength; obesity; physical activity; pregnancy diabetes mellitus; waist circumference; Adult; Aged; Body Mass Index; Diabetes Mellitus, Type 2; Female; Homeostasis; Humans; Insulin Resistance; Male; Metabolic Syndrome X; Middle Aged; Muscle Strength; Physical Fitness; Predictive Value of Tests; Regression Analysis; Risk Factors; Waist Circumference; Young Adult
[SDGs]SDG3
Appears in Collections:醫學系

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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

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