https://scholars.lib.ntu.edu.tw/handle/123456789/346628
DC 欄位 | 值 | 語言 |
---|---|---|
dc.creator | 林宜長;石東生;熊映美 | zh-tw |
dc.creator | Hsiao, P.-K. and Lin, Y.-C. and Shih, T.-S. and Chiung, Y.-M. | - |
dc.creator | LIN, YI-CHANG;SHIH, TUNG-SHENG;CHIUNG, YIN-MEI | en |
dc.date.accessioned | 2018-09-10T07:26:01Z | - |
dc.date.available | 2018-09-10T07:26:01Z | - |
dc.date.issued | 2009 | - |
dc.identifier.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-76749118533&partnerID=MN8TOARS | - |
dc.identifier.uri | http://scholars.lib.ntu.edu.tw/handle/123456789/346628 | - |
dc.description.abstract | Purpose: To investigate the effects of 1,4-dichlorobenzene (1,4-DCB) on kidney, liver, and hematological functions of workers in insect repellent factories in Taiwan. Methods: A cross-sectional study was performed comparing 46 exposed workers and 29 non-exposed workers. Health information was collected using questionnaires and biochemical tests. The concentration of urinary 2,5-dichlorophenol (2,5-DCP), the major metabolite of 1,4-DCB, was analyzed by gas chromatography with electron-capture detection. Results: Urinary 2,5-DCP concentration, white blood cell (WBC) count, and serum alanine aminotransferase (ALT) level were higher in exposed workers than in non-exposed ones (P < 0.05). Furthermore, the WBC count and ALT level were significantly correlated with the concentration of 2,5-DCP in urine (P < 0.05). The blood urea nitrogen was significantly higher in on-site exposed workers (P < 0.05). Urinary 2,5-DCP concentration was significantly lower in workers who wore personal protective equipment (PPE) during work than in those who did not (P < 0.05). Conclusions: The higher urinary 2,5-DCP concentration in exposed (105.38 μg/L) than non-exposed (1.08 μg/L) workers suggests that 1,4-DCB exposure may increase the 2,5-DCP concentration in urine. Moreover, exposure to 1,4-DCB may also increase WBC count and ALT activity, and PPE may protect workers from 1,4-DCB exposure. ? 2009 Springer-Verlag. | - |
dc.language | en | en |
dc.relation.ispartof | International Archives of Occupational and Environmental Health | en_US |
dc.source | AH | - |
dc.subject | 1,4-Dichlorobenzene; Health effect; Occupational exposure; Urine analysis | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | 2,5 dichlorophenol; 2,5-dichlorophenol; 4 dichlorobenzene; 4-dichlorobenzene; alanine aminotransferase; chlorobenzene; chlorophenol; insect repellent; 2,5 dichlorophenol; adult; article; blood; cross-sectional study; drug effect; female; human; kidney; leukocyte count; liver; male; metabolism; middle aged; occupational exposure; Taiwan; urea nitrogen blood level; urine; Adult; Alanine Transaminase; Blood Urea Nitrogen; Chlorobenzenes; Chlorophenols; Cross-Sectional Studies; Female; Humans; Insect Repellents; Kidney; Leukocyte Count; Liver; Male; Middle Aged; Occupational Exposure; Taiwan; Young Adult; Hexapoda | - |
dc.title | Effects of occupational exposure to 1,4-dichlorobenzene on hematologic, kidney, and liver functions | - |
dc.type | journal article | en |
dc.identifier.doi | 10.1007/s00420-009-0398-5 | - |
dc.relation.pages | 1077-1085 | - |
dc.relation.journalvolume | 82 | - |
dc.relation.journalissue | 9 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
顯示於: | 環境與職業健康科學研究所 |
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