https://scholars.lib.ntu.edu.tw/handle/123456789/354258
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | HSIN-YUN SUN | en |
dc.creator | Sun, H.-Y. and Cacciarelli, T.V. and Singh, N. | - |
dc.date.accessioned | 2018-09-10T08:02:48Z | - |
dc.date.available | 2018-09-10T08:02:48Z | - |
dc.date.issued | 2010 | - |
dc.identifier.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-75449098274&partnerID=MN8TOARS | - |
dc.identifier.uri | http://scholars.lib.ntu.edu.tw/handle/123456789/354258 | - |
dc.description.abstract | Whether pretransplant nonviral infections influence outcomes after transplantation in liver transplant recipients in the current era is not well defined. One hundred consecutive patients undergoing liver transplantation in 2005-2008 were studied. Demographics, posttransplant clinical events, and mortality were compared between recipients with and without infections within 12 months before transplantation. In all, 32% of the patients (32/100) developed 45 episodes of pretransplant infections, which included spontaneous bacterial peritonitis (35.6%), bloodstream infections (28.9%), cellulitis (13.3%), pneumonia (8.9%), urinary tract infections (6.7%), and other infections (6.7%). Compared with 68 recipients without pretransplant infections, those with infections had a higher Model for End-Stage Liver Disease score and a lower likelihood of transplantation from home and required longer and more frequent hospital care before and after transplantation (P < 0.05). Mortality at 90 (9.4% versus 2.9%) and 180 days (15.6% versus 10.3%) post-transplant did not differ significantly between recipients with and without pretransplant infections (P = not significant). A higher Model for End-Stage Liver Disease score (P < 0.05) and posttransplant infections (P < 0.05 and P < 0.001), but not pretransplant infections, were associated with posttransplant mortality at 90 and 180 days. In conclusion, pretransplant infections that have been adequately treated do not pose a significant risk for poor outcomes, including posttransplant mortality. ? 2010 AASLD. | - |
dc.language | en | en |
dc.relation.ispartof | Liver Transplantation | en_US |
dc.source | AH | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | ampicillin; cefotaxime; ganciclovir; methylprednisolone; prednisone; sulfamethoxazole; tacrolimus; trimethoprim; valganciclovir; adult; aged; antibiotic prophylaxis; article; bacterial peritonitis; bloodstream infection; candidiasis; cellulitis; controlled study; corticosteroid therapy; cytomegalovirus infection; demography; enterococcal infection; Escherichia coli infection; female; graft recipient; Gram negative infection; hepatitis C; hospital care; hospital readmission; human; intensive care unit; intubation; Klebsiella pneumoniae infection; liver graft; liver graft rejection; liver transplantation; low drug dose; major clinical study; male; outcome assessment; Pneumocystis pneumonia; pneumonia; postoperative care; postoperative infection; preoperative evaluation; priority journal; recurrent infection; reoperation; repeat procedure; scoring system; spontaneous bacterial peritonitis; Streptococcus infection; surgical mortality; urinary tract infection; vancomycin resistant Enterococcus; Adult; Aged; Bacterial Infections; Cellulitis; Comorbidity; Female; Humans; Liver Failure; Liver Transplantation; Male; Middle Aged; Pneumonia, Bacterial; Preoperative Period; Risk Factors; Urinary Tract Infections | - |
dc.title | Impact of pretransplant infections on clinical outcomes of liver transplant recipients | - |
dc.type | journal article | en |
dc.identifier.doi | 10.1002/lt.21982 | - |
dc.relation.pages | 222-228 | - |
dc.relation.journalvolume | 16 | - |
dc.relation.journalissue | 2 | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
顯示於: | 醫學系 |
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