https://scholars.lib.ntu.edu.tw/handle/123456789/357844
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Tsai, M.-R. | en_US |
dc.contributor.author | Chiu, Y.-W. | en_US |
dc.contributor.author | Lo, M.T. | en_US |
dc.contributor.author | CHI-KUANG SUN | en_US |
dc.date.accessioned | 2018-09-10T08:14:01Z | - |
dc.date.available | 2018-09-10T08:14:01Z | - |
dc.date.issued | 2010 | - |
dc.identifier.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-77956620475&partnerID=MN8TOARS | - |
dc.identifier.uri | http://scholars.lib.ntu.edu.tw/handle/123456789/357844 | - |
dc.description.abstract | Atrial fibrillation (AF) is the most common irregular heart rhythm and the mortality rate for patients with AF is approximately twice the mortality rate for patients with normal sinus rhythm (NSR). Some research has indicated that myocardial fibrosis plays an important role in predisposing patients to AF. Therefore, realizing the relationship between myocardial collagen fibrosis and AF is significant. Second-harmonic generation (SHG) is an optically nonlinear coherent process to image the collagen network. We perform SHG microscopic imaging of the collagen fibers in the human atrial myocardium. Utilizing the SHG images, we can identify the differences in morphology and the arrangement of collagen fibers between NSR and AF tissues. We also quantify the arrangement of the collagen fibers using Fourier transform images and calculating the values of angle entropy. We indicate that SHG imaging, a nondestructive and reproducible method to analyze the arrangement of collagen fibers, can provide explicit information about the relationship between myocardial fibrosis and AF. ? 2010 Society of Photo-Optical Instrumentation Engineers. | - |
dc.language | en | en |
dc.relation.ispartof | Journal of Biomedical Optics | en_US |
dc.source | AH-Scopus to ORCID | - |
dc.subject | Atrial fibrillation; Collagen; Fourier transform image; Second-harmonic generation | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | Atrial fibrillation; Collagen fiber; Explicit information; Fourier; Microscopic imaging; Mortality rate; Myocardial fibrosis; Non destructive; Nonlinear coherent process; Normal sinus rhythm; Diseases; Fibers; Fourier transforms; Harmonic analysis; Harmonic generation; Microscopic examination; Tissue; Collagen; fibrillar collagen; article; equipment; equipment design; fluorescence microscopy; heart atrium fibrillation; heart muscle; human; instrumentation; methodology; pathology; reproducibility; sensitivity and specificity; ultrastructure; Atrial Fibrillation; Equipment Design; Equipment Failure Analysis; Fibrillar Collagens; Humans; Microscopy, Fluorescence; Myocardium; Reproducibility of Results; Sensitivity and Specificity | - |
dc.title | Second-harmonic generation imaging of collagen fibers in myocardium for atrial fibrillation diagnosis | - |
dc.type | journal article | en |
dc.identifier.doi | 10.1117/1.3365943 | - |
dc.relation.journalvolume | 15 | - |
dc.relation.journalissue | 2 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Biomedical Electronics and Bioinformatics | - |
crisitem.author.dept | Electrical Engineering | - |
crisitem.author.dept | Photonics and Optoelectronics | - |
crisitem.author.orcid | 0000-0002-4467-2509 | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
顯示於: | 電機工程學系 |
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