|dc.contributor.author||Lin, Shoei Long||en|
|dc.creator||Hsieh, Chen-Hsi;Kuo, Ying-Shiung;Liao, Li-Jen;Hu, Kawang-Yu;Lin, Shih-Chiang;Wu, Le-Jung;Lin, Yu-Chin;Chen, Yu-Jen;Wang, Li-Ying;Hsieh, Yen-Ping;Lin, Shoei Long;Chen, Chun-Yi;Chen, Chien-An;Shueng, Pei-Wei||en|
|dc.creator||Hsieh, C.-H. and Kuo, Y.-S. and Liao, L.-J. and Hu, K.-Y. and Lin, S.-C. and Wu, L.-J. and Lin, Y.-C. and Chen, Y. and Wang, L.-Y. and Hsieh, Y.-P. and Lin, S.L. and Chen, C.-Y. and Chen, C.-A. and Shueng, P.-W.||-|
|dc.description.abstract||Background: The aim of this study was to assess the treatment results and toxicity profiles of helical tomotherapy (HT) for postoperative high-risk oral cavity cancer.Methods: From December 6, 2006 through October 9, 2009, 19 postoperative high-risk oral cavity cancer patients were enrolled. All of the patients received HT with (84%) or without (16%) chemotherapy.Results: The median follow-up time was 17 months. The 2-year overall survival, disease-free survival, locoregional control, and distant metastasis-free rates were 94%, 84%, 92%, and 94%, respectively. The package of overall treatment time > 13 wk, the interval between surgery and radiation ? 6 wk, and the overall treatment time of radiation ? 7 wk was 21%, 84%, and 79%, respectively. The percentage of grade 3 mucositis, dermatitis, and leucopenia was 42%, 5% and 5%, respectively.Conclusions: HT achieved encouraging clinical outcomes for postoperative high-risk oral cavity cancer patients with high compliance. A long-term follow-up study is needed to confirm these preliminary findings. ? 2011 Hsieh et al; licensee BioMed Central Ltd.||-|
|dc.subject.other||cisplatin; fluorouracil; folinic acid; antineoplastic agent; adult; aged; anemia; article; cancer control; cancer survival; chemoradiotherapy; clinical article; controlled study; dermatitis; disease free survival; distant metastasis; female; human; intensity modulated radiation therapy; leukopenia; male; mouth cancer; mucosa inflammation; oral surgery; overall survival; patient compliance; postoperative care; retrospective study; thrombocytopenia; tomotherapy; treatment outcome; weight reduction; xerostomia; clinical trial; drug effect; intensity modulated radiation therapy; leukopenia; methodology; middle aged; mouth; mouth tumor; mucosa inflammation; multimodality cancer therapy; postoperative care; radiation dermatitis; radiation dose; radiation exposure; risk factor; spiral computer assisted tomography; Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Leukopenia; Male; Middle Aged; Mouth; Mouth Neoplasms; Mucositis; Postoperative Care; Radiodermatitis; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Risk Factors; Tomography, Spiral Computed; Treatment Outcome; Young Adult||-|
|dc.title||Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer||-|
|Appears in Collections:||物理治療學系所|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.