|Title:||Prostate cancer mortality in Taiwanese men: Increasing age-standardized trend in general population and increased risk in diabetic men||Authors:||CHIN-HSIAO TSENG
|Issue Date:||2011||Journal Volume:||43||Journal Issue:||2||Start page/Pages:||142-150||Source:||Annals of Medicine||Abstract:||
Background. To evaluate the trend of prostate cancer mortality in Taiwanese general population and the association between diabetes and prostate cancer mortality. Materials and methods. In the general population during 19952006, the trends of prostate cancer mortality were evaluated, followed by calculation of age-specific mortality rates for age 4064, 6574, and ? 75 years. A cohort of 102,651 diabetic men aged ? 40 years recruited in 19951998 was followed prospectively. Results. The trends of crude and age-standardized mortality from prostate cancer in the general population increased significantly (P < 0.0001). In the general population, 7,966 men aged ? 40 years died of prostate cancer, and aging was associated with increased risk. Age-specific prostate cancer mortality suggested significantly increasing trend for ages 6574 and ? 75 years. A total of 321 diabetic men died of prostate cancer (crude mortality rate 41.9/100,000 person-years). Mortality rate ratios (95% confidence interval) showed higher risk of prostate cancer mortality in the diabetic patients, with magnitude increased with decreasing age: 1.55 (1.291.86), 2.68 (2.293.13), and 6.84 (5.348.75) for age ? 75, 6574, and 4064 years, respectively. Conclusions. Prostate cancer mortality in the Taiwanese general population is increasing. Diabetic patients have a higher risk of prostate cancer mortality, which is more remarkable with decreasing age. ? 2011 Informa UK, Ltd.
|DOI:||10.3109/07853890.2010.530683||metadata.dc.subject.other:||adult; age; aged; article; calculation; cancer mortality; clinical evaluation; cohort analysis; diabetes mellitus; disease association; human; major clinical study; male; population; priority journal; prospective study; prostate cancer; risk; Taiwan; Adult; Age Factors; Aged; Asian Continental Ancestry Group; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Follow-Up Studies; Humans; Male; Middle Aged; Mortality; Prospective Studies; Prostatic Neoplasms; Risk Factors; Taiwan
|Appears in Collections:||醫學系|
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