Biodegradation and bio-sorption of antibiotics and non-steroidal anti-inflammatory drugs using immobilized cell process
Journal
Chemosphere
Journal Volume
84
Journal Issue
9
Pages
1216-1222
Date Issued
2011
Author(s)
Yu, Tsung-Hsien
Lin, Angela Yu-Chen
Panchangam, Sri Ch
ana
Hong, Pui-Kwan
y
Yang, Ping-Yi
Lin, Cheng-Fang
Abstract
In the present study, the removal mechanisms of four antibiotics (sulfamethoxazole, sulfadimethoxine, sulfamethazine, and trimethoprim) and four non-steroidal anti-inflammatory drugs (acetaminophen, ibuprofen, ketoprofen, and naproxen) in immobilized cell process were investigated using batch reactors. This work principally explores the individual or collective roles of biodegradation and bio-sorption as removal routes of the target pharmaceuticals and the results were validated by various experimental and analytical tools. Biodegradation and bio-sorption were found as dominant mechanisms for the drug removal, while volatilization and hydrolysis were negligible for all target pharmaceuticals. The target pharmaceuticals responded to the two observed removal mechanisms in different ways, typically: (1) strong biodegradability and bio-sorption by acetaminophen, (2) strong biodegradability and weak bio-sorption by sulfamethoxazole, sulfadimethoxine, ibuprofen and naproxen, (3) low biodegradability and weak bio-sorption by sulfamethazine and ketoprofen, and (4) low biodegradability and medium bio-sorption by trimethoprim. In the sorption/desorption experiment, acetaminophen, sulfamethoxazole and sulfadimethoxine were characterized by strong sorption and weak desorption. A phenomenon of moderate sorption and well desorption was observed for sulfamethazine, trimethoprim and naproxen. Both ibuprofen and ketoprofen were weakly sorbed and strongly desorbed. © 2011 Elsevier Ltd.
Subjects
Antibiotics; Bio-sorption; Biodegradation; Immobilized cell bio-carrier process; Non-steroidal anti-inflammatory drugs
SDGs
Other Subjects
Batch reactors; Biodegradability; Biodegradation; Cell culture; Cells; Desorption; Bio-carriers; Dominant mechanism; Immobilized cells; Non-steroidal anti-inflammatory drugs; Removal mechanism; Sorption/Desorption; Sulfadimethoxine; Sulfamethoxazole; Antibiotics; antibiotic agent; ketoprofen; naproxen; nonsteroid antiinflammatory agent; paracetamol; sulfadimethoxine; sulfadimidine; sulfamethoxazole; trimethoprim; antibiotics; biodegradation; cell organelle; desorption; drug; experimental study; hydrolysis; immobilization; observational method; pollutant removal; sorption; steroid; volatilization; analytic method; article; batch reactor; biodegradability; biodegradation; biosorption; biotransformation; controlled study; desorption; hydrolysis; immobilized cell; volatilization; waste water management
Type
journal article