https://scholars.lib.ntu.edu.tw/handle/123456789/363235| Title: | Biocompatible, surface functionalized mesoporous titania nanoparticles for intracellular imaging and anticancer drug delivery | Authors: | Wu, K.C.-W. Yamauchi, Y. Hong, C.-Y. Yang, Y.-H. Liang, Y.-H. Funatsu, T. Tsunoda, M. KEVIN CHIA-WEN WU |
Issue Date: | 2011 | Journal Volume: | 47 | Journal Issue: | 18 | Start page/Pages: | 5232-5234 | Source: | Chemical Communications | Abstract: | Mesoporous titania nanoparticles (MTNs) with excellent biocompatibility (LC50 ? 400 μg mL?1) and a large surface area (ca. 237.3 m2 g?1) were synthesized and further functionalized with a phosphate-containing fluorescent molecule (i.e. flavin mononucleotide; FMN) and loaded with an anticancer drug (i.e. Doxorubicin) for successful intracellular bioimaging and drug delivery, respectively, in human breast cancer cells BT-20. ? The Royal Society of Chemistry 2011. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-79954600725&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/363235 |
DOI: | 10.1039/c1cc10659g | SDG/Keyword: | doxorubicin; flavine mononucleotide; mesoporous titania nanoparticle; nanoparticle; phosphate; pralidoxime mesilate; titanium derivative; titanium dioxide; unclassified drug; article; biocompatibility; breast cancer; cancer cell; cell proliferation; controlled study; cytotoxicity; drug delivery system; female; human; human cell; porosity; surface property; transmission electron microscopy [SDGs]SDG3 |
| Appears in Collections: | 化學工程學系 |
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