https://scholars.lib.ntu.edu.tw/handle/123456789/367316
標題: | Early-life indoor environmental exposures increase the risk of childhood asthma | 作者: | YUNG-LING LEE | 關鍵字: | Asthma; Cockroach; Environmental tobacco smoke; Moulds; Pet | 公開日期: | 2011 | 卷: | 215 | 期: | 1 | 起(迄)頁: | 19-25 | 來源出版物: | International Journal of Hygiene and Environmental Health | 摘要: | We aim to explore the relationships between exposure to dampness, pets, and environmental tobacco smoke (ETS) early in life and asthma in Taiwanese children, and to discuss their links to early- and late-onset asthma. We conducted a 1:2 matched case-control study from the Taiwan Children Health Study, which was a nationwide study that recruited 12-to-14 year-old school children in 14 communities. The 579 mothers of the participants were interviewed by telephone about their children's environmental exposures before they were 5 years old, including the in-utero period. Childhood asthma was associated with exposure to early life environmental factors, such as cockroaches (OR = 2.16; 95% CI, 1.15-4.07), visible mould (OR = 1.75; 95% CI, 1.15-2.67), mildewy odors (OR = 5.04; 95% CI, 2.42-10.50), carpet (OR = 2.36; 95% CI, 1.38-4.05), pets (OR = 2.11; 95% CI, 1.20-3.72), and more than one hour of ETS per day (OR = 1.93; 95% CI, 1.16-3.23). The ORs for mildewy odors, feather pillows, and ETS during early childhood were greater among children with late-onset asthma. Cockroaches, carpet, pets, and in-utero exposures to ETS affected the timing of early-onset asthma. Exposure to these factors led to dose-responsiveness in the risk of asthma. And the earlier exposures may trigger the earlier onset. Interventions in avoiding these environmental exposures are necessary for early-prevention of childhood asthma. ? 2011 Elsevier GmbH. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-82155173507&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/367316 |
DOI: | 10.1016/j.ijheh.2011.07.004 | SDG/關鍵字: | adolescent; air pollutant; animal; article; asthma; bed; building; case control study; child; cockroach; environmental exposure; feather; female; fungus; human; indoor air pollution; interview; male; mother; passive smoking; pet animal; pregnancy; prenatal exposure; risk; risk factor; Taiwan; Adolescent; Air Pollutants; Air Pollution, Indoor; Animals; Asthma; Bedding and Linens; Case-Control Studies; Child; Cockroaches; Environmental Exposure; Feathers; Female; Floors and Floorcoverings; Fungi; Humans; Interviews as Topic; Male; Mothers; Odds Ratio; Pets; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Taiwan; Tobacco Smoke Pollution; Animalia; Blattaria; Nicotiana tabacum |
顯示於: | 流行病學與預防醫學研究所 |
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