|Title:||Self-reported psychopathology and health-related quality of life in heroin users treated with methadone||Authors:||LI-REN CHANG
Chang, Hung-Chieh Wu
|Keywords:||BriefSymptom rating scale; Heroin abuse; World health organization questionnaire on quality of life||Issue Date:||2012||Journal Volume:||9||Journal Issue:||1||Start page/Pages:||41-48||Source:||Neuropsychiatric Disease and Treatment||Abstract:||
Background: Health-related quality of life (HRQoL) remains poor among heroin users, even after being treated with methadone. Evidence regarding self-reported psychopathology and HRQoL in heroin users is also limited. The present study aimed to investigate the association between self-reported psychopathology and HRQoL in Asian heroin users treated with methadone. Methods: Thirty-nine heroin users treated with methadone and 39 healthy controls were recruited. Both groups self-reported on demographic data, the Brief Symptom Rating Scale, EuroQoL-5D, and World Health Organization Questionnaire on Quality of Life: Short Form. We compared clinical characteristics, psychopathology, and HRQoL between the two study groups. Correlation and regression analyses were conducted to explore the association between psychopathology and HRQoL in the heroin user group. Results: Heroin users had more psychopathology and worse HRQoL than healthy controls. The HRQoL of heroin users had significant correlations with Brief Symptom Rating Scale scores. HRQoL could be predicted by depression, anxiety, paranoia, and additional symptoms (i.e., poor appetite and sleep difficulties) independently. Conclusion: Self-reported psychopathology, depression, anxiety, paranoia, poor appetite, and sleep difficulties had a negative impact on each domain of HRQoL among heroin users treated with methadone. The importance of the environmental domain of HRQoL is discussed. Clinicians should recognize comorbid psychiatric symptoms early on to improve HRQoL in heroin users. ? 2013 Chen et al, publisher and licensee Dove Medical Press Ltd.
|DOI:||10.2147/NDT.S37284||SDG/Keyword:||methadone; adult; alcohol consumption; anorexia; anxiety; article; Brief Symptom Inventory; clinical article; clinical feature; comorbidity; controlled study; demography; depression; DSM-IV; female; health status; heroin dependence; human; informed consent; male; mental disease; paranoia; pilot study; quality of life; questionnaire; rating scale; self report; sleep disorder; Symptom Checklist 90; Taiwan; visual analog scale; world health organization
|Appears in Collections:||醫學系|
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