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  1. NTU Scholars
  2. 醫學院
  3. 醫學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/367814
Title: Self-reported psychopathology and health-related quality of life in heroin users treated with methadone
Authors: LI-REN CHANG 
Chen, Ying-Zai
Huang, Wei-Lieh
Shan, Jia-Chi
Lin, Yu-Hsuan
Chang, Hung-Chieh Wu
Chang, Li-Ren 
Keywords: BriefSymptom rating scale; Heroin abuse; World health organization questionnaire on quality of life
Issue Date: 2012
Journal Volume: 9
Journal Issue: 1
Start page/Pages: 41-48
Source: Neuropsychiatric Disease and Treatment 
Abstract: 
Background: Health-related quality of life (HRQoL) remains poor among heroin users, even after being treated with methadone. Evidence regarding self-reported psychopathology and HRQoL in heroin users is also limited. The present study aimed to investigate the association between self-reported psychopathology and HRQoL in Asian heroin users treated with methadone. Methods: Thirty-nine heroin users treated with methadone and 39 healthy controls were recruited. Both groups self-reported on demographic data, the Brief Symptom Rating Scale, EuroQoL-5D, and World Health Organization Questionnaire on Quality of Life: Short Form. We compared clinical characteristics, psychopathology, and HRQoL between the two study groups. Correlation and regression analyses were conducted to explore the association between psychopathology and HRQoL in the heroin user group. Results: Heroin users had more psychopathology and worse HRQoL than healthy controls. The HRQoL of heroin users had significant correlations with Brief Symptom Rating Scale scores. HRQoL could be predicted by depression, anxiety, paranoia, and additional symptoms (i.e., poor appetite and sleep difficulties) independently. Conclusion: Self-reported psychopathology, depression, anxiety, paranoia, poor appetite, and sleep difficulties had a negative impact on each domain of HRQoL among heroin users treated with methadone. The importance of the environmental domain of HRQoL is discussed. Clinicians should recognize comorbid psychiatric symptoms early on to improve HRQoL in heroin users. ? 2013 Chen et al, publisher and licensee Dove Medical Press Ltd.
URI: http://www.scopus.com/inward/record.url?eid=2-s2.0-84872090213&partnerID=MN8TOARS
http://scholars.lib.ntu.edu.tw/handle/123456789/367814
DOI: 10.2147/NDT.S37284
SDG/Keyword: methadone; adult; alcohol consumption; anorexia; anxiety; article; Brief Symptom Inventory; clinical article; clinical feature; comorbidity; controlled study; demography; depression; DSM-IV; female; health status; heroin dependence; human; informed consent; male; mental disease; paranoia; pilot study; quality of life; questionnaire; rating scale; self report; sleep disorder; Symptom Checklist 90; Taiwan; visual analog scale; world health organization
[SDGs]SDG3
Appears in Collections:醫學系

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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
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開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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