https://scholars.lib.ntu.edu.tw/handle/123456789/368830
標題: | Effects of breathing frequency on baroreflex effectiveness index and spontaneous baroreflex sensitivity derived by sequence analysis. | 作者: | YONG-PING WANG Kuo, Terry B.J. Lai, Chun-Ting Lee, Guo-She Yang, Cheryl C.H. |
關鍵字: | baroreflex; parasympathetic nervous system; respiration; respiratory rate | 公開日期: | 十一月-2012 | 卷: | 30 | 期: | 11 | 起(迄)頁: | 2151 | 來源出版物: | Journal of Hypertension | 摘要: | AIMS: High-frequency paced breathing is required to avoid overestimation when measuring spectral baroreflex sensitivity (BRSLF) to predict outcomes in cardiovascular patients. We examined whether respiration should also be controlled when measuring the baroreflex effectiveness index (BEI) and baroreflex sensitivity (BRSseq), which are derived by sequence analysis. METHODS: We studied 17 healthy young adults who breathed spontaneously and controlled their breathing to rates of 0.1, 0.2, 0.3 and 0.4 Hz in the supine position. We found respiratory influences on BEI and BRSseq depended on the lag used to pair the systolic arterial pressure and R-R interval in a sequence. Therefore, the two baroreflex measures were obtained by selecting the lag with a larger number of sequences for each section. RESULTS: BEI decreased progressively as the breathing frequency increased. BRSseq remained unchanged at rates of 0.1, 0.2 and 0.3 Hz, but was reduced during 0.4 Hz breathing. In contrast, BRSLF was constant during 0.2, 0.3, and 0.4 Hz breathing, but was greater at 0.1 Hz. Rates of spontaneous breathing range from 0.1 to 0.32 Hz with a mean value of 0.19 Hz. Baroreflex measures obtained for spontaneous breathing were found to be between the values for 0.1 and 0.3 Hz paced breathing. CONCLUSION: BEI and BRSseq do not remain constant at various breathing frequencies. Nonetheless, considering the pattern of change and the frequency range of spontaneous respiration, the authors suggest that high-frequency paced breathing is not necessary when measuring the BEI and BRSseq under the conditions used in this study. Copyright ? 2012 Lippincott Williams &Wilkins. |
URI: | http://europepmc.org/abstract/med/22990351 http://scholars.lib.ntu.edu.tw/handle/123456789/368830 |
DOI: | 10.1097/HJH.0b013e328357ff46 | SDG/關鍵字: | adult; article; breathing rate; female; human; human experiment; male; normal human; pressoreceptor reflex; priority journal; sequence analysis; supine position; systolic blood pressure |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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