Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Bioresources and Agriculture / 生物資源暨農學院
  3. School of Veterinary Medicine / 獸醫專業學院
  4. Veterinary Medicine / 獸醫學系
  5. Application of autologous mesenchymal stem cells and coenzyme Q10 in a pig model of acute myocardial infarction
 
  • Details

Application of autologous mesenchymal stem cells and coenzyme Q10 in a pig model of acute myocardial infarction

Journal
Journal of Animal and Veterinary Advances
Journal Volume
11
Journal Issue
19
Pages
3581-3587
Date Issued
2012
Author(s)
Lin, S.-C.
TZONG-FU KUO  
Huang, F.-J.
Chang, T.-C.
Hsuuw, Y.-D.
DOI
10.3923/javaa.2012.3581.3587
URI
http://www.scopus.com/inward/record.url?eid=2-s2.0-84874556530&partnerID=MN8TOARS
http://scholars.lib.ntu.edu.tw/handle/123456789/369621
Abstract
The application of antioxidants in order to decrease injures of implanted cells has been an important issue for transplantation therapy. Coenzyme Q10 is widely distributed in animals and humans. It plays an important role in cellular energy production in the mitochondrial respiratory chain. Coenzyme Q10 has been demonstrated to have a potential role in the prevention and treatment of heart diseases by improving cellular bioenergetics. Mesechymal stem cells are a leading candidate for cell-based therapies. Researchers hypothesized that the condition of damaged myocardium could be improved with coenzyme Q10 supplementation therapy. Cell survival rate would be increased due in part to the decreased apoptosis and necrosis of cardiomyocytes in ischemic and reperfusion injures. In this study, a combination therapy of mesechymal stem cells transplantation and coenzyme Ql 0 supplementation for acute myocardial infarct showed promising results in vivo. Left ventricular function was notably improved with only small areas of fibrosis formation. ? Medwell Journals, 2012.
Subjects
Acute myocardial infarction; Cells therapy; Coenzyme Q10; Ischemic; Mesenchymal stem cell; Reperfusion injures
SDGs

[SDGs]SDG3

Type
journal article

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science