Magnetic control system targeted for capsule endoscopic operations in the stomach - Design, fabrication, and in vitro and ex vivo evaluations
Journal
IEEE Transactions on Biomedical Engineering
Journal Volume
59
Journal Issue
7
Pages
2068-2079
Date Issued
2012
Author(s)
Lien, G.-S.
CHIH-WEN LIU
Chuang, C.-L.
Teng, M.-T.
Abstract
This paper presents a novel solution of a hand-held external controller to a miniaturized capsule endoscope in the gastrointestinal (GI) tract. Traditional capsule endoscopes move passively by peristaltic wave generated in the GI tract and the gravity, which makes it impossible for endoscopists to manipulate the capsule endoscope to the diagnostic disease areas. In this study, the main objective is to present an endoscopic capsule and a magnetic field navigator (MFN) that allows endoscopists to remotely control the locomotion and viewing angle of an endoscopic capsule. The attractive merits of this study are that the maneuvering of the endoscopic capsule can be achieved by the external MFN with effectiveness, low cost, and operation safety, both from a theoretical and an experimental point of view. In order to study the magnetic interactions between the endoscopic capsule and the external MFN, a magnetic-analysis model is established for computer-based finite-element simulations. In addition, experiments are conducted to show the control effectiveness of the MFN to the endoscopic capsule. Finally, several prototype endoscopic capsules and a prototype MFN are fabricated, and their actual capabilities are experimentally assessed via in vitro and ex vivo tests using a stomach model and a resected porcine stomach, respectively. Both in vitro and ex vivo test results demonstrate great potential and practicability of achieving high-precision rotation and controllable movement of the capsule using the developed MFN. ? 1964-2012 IEEE.
Subjects
Capsule endoscope (CN); ex vivo; gastrointestinal (GI) endoscopy; in vitro; locomotion; magnetic field
SDGs
Other Subjects
Capsule endoscopes; Control effectiveness; Endoscopic capsule; Endoscopic operations; Ex-vivo; External controller; Finite element simulations; Gastrointestinal endoscopies; Gastrointestinal tract; GI tract; High-precision; In-vitro; Low costs; Magnetic control systems; Magnetic interactions; Operation safety; Peristaltic waves; Viewing angle; Biped locomotion; Computer aided analysis; Computer simulation; Finite element method; Magnetic fields; Endoscopy; abdominal wall; accuracy; article; capsule endoscopy; clinical effectiveness; computer simulation; cost; devices; ex vivo study; finite element analysis; gastrointestinal tract; human; in vitro study; large intestine; locomotion; magnetic field; magnetic field navigator; magnetism; nonhuman; safety; small intestine; stomach; torque; Animals; Capsule Endoscopes; Capsule Endoscopy; Electromagnetic Fields; Equipment Design; Feasibility Studies; Gastroscopy; Humans; Models, Biological; Stomach; Swine; Torque
Type
journal article