https://scholars.lib.ntu.edu.tw/handle/123456789/370573
標題: | Functional acrylic acid as stabilizer for synthesis of smart hydrogel particles containing a magnetic Fe 3O 4 core | 作者: | WEN-YEN CHIU | 關鍵字: | Core-shell structure; N-Isopropylacrylamide | 公開日期: | 2012 | 卷: | 53 | 期: | 14 | 起(迄)頁: | 2839-2846 | 來源出版物: | Polymer (United Kingdom) | 摘要: | This paper reports a novel method to synthesize magnetic, stimuli-sensitive latex nanoparticles made with magnetite/poly(N-isopropylacrylamide-co-acrylic acid) (Fe3O4/P(NIPAAm-co-AAc)). To form a stabilized suspended core, iron oxide (Fe3O4) was functionalized with AAc such that further polymerization with NIPAAm and AAc monomers could occur. The P(NIPAAm-co-AAc) shell layer exhibited thermosensitive properties. The inclusion of Fe3O4 into the latex nanoparticles was confirmed using transmission electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction spectroscopy, thermogravimetric analyzer (TGA), and superconducting quantum interference device magnetometer. The NIP-(AAc2.6-Fe) latex nanoparticles contained 2.25% Fe3O4 (by weight), as determined by TGA analysis. The particle diameters measured approximately 160-240 nm with a lower critical solution temperature of 35°C. These novel magnetic stimuli-responsive latex nanoparticles have potential applications in numerous fields, such as catalyst supports, protein immobilization, cancer therapy, target drug delivery systems, and other biomedical applications. ? 2011 Elsevier Ltd. All rights reserved. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84862017888&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/370573 |
DOI: | 10.1016/j.polymer.2012.05.010 | SDG/關鍵字: | Acrylic monomers; Amides; Carboxylic acids; High resolution transmission electron microscopy; Hydrogels; Iron oxides; Latexes; Magnetite; Magnetite nanoparticles; Medical applications; Nanomagnetics; Quantum interference devices; SQUIDs; Synthesis (chemical); Targeted drug delivery; Transmission electron microscopy; X ray diffraction; Biomedical applications; Core shell structure; Lower critical solution temperature; N- isopropylacrylamide; Protein immobilization; Superconducting quantum interference; Thermo-sensitive properties; Thermogravimetric analyzers; X ray photoelectron spectroscopy |
顯示於: | 化學工程學系 |
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