|Title:||Allergic predisposition modifies the effects of pet exposure on respiratory disease in boys and girls: The seven northeast cities of china (snecc) study||Authors:||YUNG-LING LEE
Lee, Yungling Leo
|Keywords:||Allergic Predisposition; Asthma; Pet exposure||Issue Date:||2012||Journal Volume:||11||Journal Issue:||1||Source:||Environmental Health: A Global Access Science Source||Abstract:||
Background: The relationship between pet exposure and the respiratory disease in childhood has been a controversial topic, much is still unknown about the nature of the associations between pet exposure and children's respiratory health stratified by gender and allergic predisposition. The objective of the present study was to assess the relationship between pet exposure and respiratory symptoms in Chinese children, and to investigate the modified effects of gender and allergic predisposition on such relationship. Methods: 31,049 children were selected from 25 districts of 7 cities in Northeast China in 2009. Information on respiratory health and exposure to home environmental factors was obtained via a standard questionnaire designed by the American Thoracic Society. Results: Children with an allergic predisposition were found to have more frequent exposure to pets than those without an allergic predisposition (18.5% vs. 15.4%). In children without an allergic predisposition, pet exposure was associated with increased susceptibility to respiratory symptoms/diseases, with girls being more susceptible than boys. No association was found between pet exposure and respiratory symptoms/diseases in boys with an allergic predisposition. In girls with an allergic predisposition, association was found between doctor-diagnosed asthma and pet exposure of their mother during pregnancy (adjusted odds ratio (ORs) = 2.03; 95% confidence interval (CI): 1.01-4.33), and their current pet exposure (ORs = 1.37; 95%CI: 1.00-1.88). Conclusions: Pet exposure in children without an allergic predisposition was associated with increased susceptibility to respiratory disease, with girls being more susceptible than boys. ? 2012 Dong et al.; licensee BioMed Central Ltd.
|DOI:||10.1186/1476-069X-11-50||SDG/Keyword:||allergy; child health; domestic species; environmental factor; questionnaire survey; respiratory disease; symptom; adolescent; allergy; article; asthma; child; China; confidence interval; controlled study; disease predisposition; female; gender; human; major clinical study; male; pet animal; pregnancy; preschool child; priority journal; questionnaire; respiratory tract disease; risk; school child; Adolescent; Animals; Child; Child, Preschool; China; Cities; Cross-Sectional Studies; Female; Genetic Predisposition to Disease; Humans; Hypersensitivity; Male; Pets; Pregnancy; Prenatal Exposure Delayed Effects; Respiratory Tract Diseases; Sex Factors; China
|Appears in Collections:||流行病學與預防醫學研究所|
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