https://scholars.lib.ntu.edu.tw/handle/123456789/374854
標題: | Gestational medication use, birth conditions, and early postnatal exposures for childhood asthma | 作者: | YUNG-LING LEE Chen, Yang-Ching Tsai, Ching-Hui Lee, Yungling |
公開日期: | 2012 | 卷: | 2012 | 來源出版物: | Clinical and Developmental Immunology | 摘要: | Our aim is to explore (1) whether gestational medication use, mode of delivery, and early postnatal exposure correlate with childhood asthma, (2) the dose responsiveness of such exposure, and (3) their links to early- and late-onset asthma. We conducted a matched case-control study based on the Taiwan Children Health Study, which was a nationwide survey that recruited 12-to-14-year-old school children in 14 communities. 579 mothers of the participants were interviewed by telephone. Exclusive breastfeeding protected children from asthma. Notably, childhood asthma was significantly associated with maternal medication use during pregnancy, vacuum use during vaginal delivery, recurrent respiratory tract infections, hospitalization, main caregiver cared for other children, and early daycare attendance. Exposure to these factors led to dose responsiveness in relationships to asthma. Most of the exposures revealed a greater impact on early-onset asthma, except for vacuum use and daycare attendance. Copyright ? 2012 Yang-Ching Chen et al. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84855573780&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/374854 |
DOI: | 10.1155/2012/913426 | SDG/關鍵字: | adolescent; article; asthma; breast feeding; caregiver; case control study; child; childhood disease; controlled study; day care; female; hospitalization; human; major clinical study; male; onset age; perinatal drug exposure; prenatal drug exposure; priority journal; recurrent disease; school child; Taiwan; upper respiratory tract infection; vacuum extraction; vaginal delivery; asthma; environmental exposure; reproductive history; risk; drug; Adolescent; Asthma; Case-Control Studies; Child; Female; Humans; Male; Maternal Exposure; Pharmaceutical Preparations; Reproductive History; Risk |
顯示於: | 流行病學與預防醫學研究所 |
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