Epicutaneous sensitization with protein antigen
Journal
Dermatologica Sinica
Journal Volume
30
Journal Issue
4
Pages
154-159
Date Issued
2012
Author(s)
Abstract
In the past few decades there has been a progressive understanding that epicutaneous sensitization with protein antigen is an important sensitization route in patients with atopic dermatitis. A murine protein-patch model has been established, and an abundance of data has been obtained from experiments using this model. This review discusses the characteristics of epicutaneous sensitization with protein antigen, the induced immune responses, the underlying mechanisms, and the therapeutic potential.
Type
journal article