https://scholars.lib.ntu.edu.tw/handle/123456789/377130
標題: | Anti-obesity activity of Lactobacillus fermented soy milk products | 作者: | TZU-MING PAN | 關鍵字: | Anti-obese activity; Daidzein; Genistein; High-fat diet (HFD); Lactobacillus paracasei subsp. paracasei NTU 101; Lactobacillus plantarum NTU 102 | 公開日期: | 2013 | 卷: | 5 | 期: | 2 | 起(迄)頁: | 905-913 | 來源出版物: | Journal of Functional Foods | 摘要: | The anti-obesity activity of Lactobacillus paracasei subsp. paracasei NTU 101 and Lactobacillus plantarum NTU 102 and their soy milk fermented products (SM101 and SM102) were investigated. Results indicated that the inhibition of 3T3-L1 differentiation and the accumulation of free fatty acids markedly increased in rats treated with SM101 and SM102. Moreover, the up-regulation and down-regulation of lipolysis and heparin-releasable lipoprotein lipase, respectively, were observed in the 3T3-L1 adipocytes of the SM101 and SM101 groups, and these effects of SM101 and SM102 were greater than unfermented soy milk (USM). We also found that SM101 and SM102 both improved obesity in Wistar rats fed with a high-fat diet (HFD) and that this improvement was stronger than that observed for USM. The level of serum leptin in HFD-induced rats was significantly elevated by the 5-week administration of SM101 and SM102 (106-1010CFU/mL per rat per day); however, this activity was not promoted by USM. The anti-obesity activity of SM101 and SM102 may result from the increased daidzein and genistein levels that were observed during the fermentation by L. paracasei subsp. paracasei NTU 101 and L. plantarum NTU 102. ? 2013 Elsevier Ltd. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84876702052&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/377130 |
DOI: | 10.1016/j.jff.2013.01.040 | SDG/關鍵字: | Glycine max; Lactobacillus; Lactobacillus paracasei; Lactobacillus paracasei subsp. paracasei; Lactobacillus plantarum; Rattus; Rattus norvegicus |
顯示於: | 生化科技學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。