https://scholars.lib.ntu.edu.tw/handle/123456789/380876
標題: | Effect of lactic fermentation on the total phenolic, saponin and phytic acid contents as well as anti-colon cancer cell proliferation activity of soymilk | 作者: | Lai, L.-R. Hsieh, S.-C. Huang, H.-Y. Chou, C.-C. SHU-CHEN HSIEH |
關鍵字: | Anticancer cell proliferative effect; Lactic fermentation; Phenolics; Phytate; Saponin; Soymilk | 公開日期: | 2013 | 卷: | 115 | 期: | 5 | 起(迄)頁: | 552-556 | 來源出版物: | Journal of Bioscience and Bioengineering | 摘要: | In an attempt to develop healthy dietary adjuncts, soymilk was fermented simultaneously with Streptococcus thermophilus 14085 and Bifidobacterium infantis 14603 at 37 °C for 24 h. It was found that lactic fermentation reduced the content of saponins and phytates, which possess antinutritional activity, and enhanced the total phenolic content as well as antitumor cell proliferation effect of soymilk against HT-29 and Caco-2 cells. The original antitumor cell component, starter organisms, and antitumor cell bioactive principles formed in soymilk during fermentation, might all have contributed to the enhanced antitumor activity of fermented soymilk. The antiproliferative effect of the extracts varied with extraction solvent. Extracts obtained from fermented soymilk with 80% methanol exhibited the highest suppression effect on the proliferation of HT-29 and Caco-2 cells. This study further stresses the potential of developing soymilk as a healthy dietary adjunct possessing enhanced anticancer activity through the use of lactic fermentation. ? 2012 The Society for Biotechnology, Japan. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84876306109&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/380876 |
DOI: | 10.1016/j.jbiosc.2012.11.022 | SDG/關鍵字: | Lactic fermentations; Phenolics; Phytate; Proliferative effects; Saponin; Soy milk; Biotechnology; Cell proliferation; Cells; Metabolites; Solvent extraction; Fermentation; lactic acid; methanol; phenol; phytic acid; saponin; antineoplastic activity; antiproliferative activity; article; Bifidobacterium longum infantis; cancer cell; cell proliferation; cell strain CACO 2; colon cancer; dietary intake; fermented product; human; human cell; human cell culture; simulation; solvent extraction; soybean milk; Streptococcus thermophilus; Bifidobacterium longum bv. Infantis; Streptococcus thermophilus |
顯示於: | 食品科技研究所 |
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