https://scholars.lib.ntu.edu.tw/handle/123456789/384583
標題: | Water-based synthesis and processing of novel biodegradable elastomers for medical applications | 作者: | Hsu, S.-H. Hung, K.-C. Lin, Y.-Y. Su, C.-H. Yeh, H.-Y. Jeng, U.-S. Lu, C.-Y. Dai, S.A. Fu, W.-E. Lin, J.-C. SHAN-HUI HSU |
公開日期: | 2014 | 卷: | 2 | 期: | 31 | 起(迄)頁: | 5083-5092 | 來源出版物: | Journal of Materials Chemistry B | 摘要: | Biodegradable elastomers in the form of polyurethane nanoparticles (NPs) were successfully synthesized based on the combinations of two hydrolysis-prone polyester diols by a green water-based process. The anionic nature of the polymers successfully rendered polyurethane NPs (30-50 nm) consisting of approximately 200-300 polymer chains. The mechanical properties and degradation rate could be adjusted by the types and ratios of the component oligodiols in the soft segment. We demonstrated the feasibility using these biodegradable NPs as building blocks to generate self-assembled morphologies in nanometric, micrometric, or bulk scale, bearing excellent elasticity and biocompatibility. The elastic NPs and their various assembled forms represent a series of smart biodegradable elastomers with potential medical applications. © 2014 the Partner Organisations. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84904414377&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/384583 |
DOI: | 10.1039/c4tb00572d | SDG/關鍵字: | Biocompatibility; Degradation; Elastomers; Mechanical properties; Medical applications; Polymers; Polyurethanes; Synthesis (chemical); Biodegradable elastomers; Building blockes; Degradation rate; Nanoparticle (NPs); Polymer chains; Self-assembled; Synthesis and processing; Water-based process; Plastics |
顯示於: | 高分子科學與工程學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。