https://scholars.lib.ntu.edu.tw/handle/123456789/391674
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | CHANG-FENG DAI | en |
dc.creator | Huang, T.-Z. and Chen, B.-W. and Huang, C.-Y. and Hwang, T.-L. and Uvarani, C. and Dai, C.-F. and Sung, P.-J. and Su, J.-H. and Sheu, J.-H. | - |
dc.date.accessioned | 2018-09-10T15:20:36Z | - |
dc.date.available | 2018-09-10T15:20:36Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-84930653674&partnerID=MN8TOARS | - |
dc.identifier.uri | http://scholars.lib.ntu.edu.tw/handle/123456789/391674 | - |
dc.description.abstract | Four new eunicellin-type hirsutalins S-V (1-4), along with a known compound (-)-6α-hydroxy polyanthellin A (5), were isolated from the soft coral Cladiella hirsuta. The structures of the metabolites were determined by extensive spectroscopic analysis. Cytotoxity of compounds 1-5 against the proliferation of a limited panel of cancer cell lines was measured. Anti-inflammatory activity of compounds 1-5 was evaluated by measuring their ability in suppressing superoxide anion generation and elastase release in fMLP/CB-induced human neutrophils. ? 2015 by the authors; licensee MDPI. | - |
dc.language | en | en |
dc.relation.ispartof | Marine Drugs | en_US |
dc.source | AH | - |
dc.subject | Anti-inflammatory activity; Cladiella hirsuta; Cytotoxic activity; Eunicellins; Soft coral | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | 6 alpha hydroxypolyanthellin A; antineoplastic agent; diterpenoid; drug metabolite; elastase; hirsutalin s; hirsutalin t; hirsutalin u; hirsutalin v; superoxide; unclassified drug; antiinflammatory agent; diterpene; eunicellin; pancreatic elastase; antiinflammatory activity; antiproliferative activity; Article; Cladiella hirsuta; controlled study; coral; drug cytotoxicity; drug determination; drug isolation; drug screening; drug structure; human; human cell; animal; Anthozoa; cell proliferation; chemistry; drug effects; metabolism; neutrophil; Alcyonacea; Cladiella; Animals; Anthozoa; Anti-Inflammatory Agents; Cell Proliferation; Diterpenes; Humans; Neutrophils; Pancreatic Elastase; Superoxides | - |
dc.title | Eunicellin-based diterpenoids, hirsutalins S-V, from the formosan soft coral Cladiella hirsuta | - |
dc.type | journal article | en |
dc.identifier.doi | 10.3390/md13052757 | - |
dc.identifier.scopus | 2-s2.0-84930653674 | - |
dc.identifier.isi | WOS:000356241100011 | - |
dc.relation.pages | 2757-2769 | - |
dc.relation.journalvolume | 13 | - |
dc.relation.journalissue | 5 | - |
item.fulltext | no fulltext | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.orcid | 0000-0003-2242-5643 | - |
顯示於: | 海洋研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。