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  4. Simple self-report FRAIL scale might be more closely associated with dialysis complications than other frailty screening instruments in rural chronic dialysis patients
 
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Simple self-report FRAIL scale might be more closely associated with dialysis complications than other frailty screening instruments in rural chronic dialysis patients

Date Issued
2015-05
Author(s)
CHIA-TER CHAO  
Hsu Y.-H.
Chang P.-Y.
He Y.-T.
Ueng R.-S.
CHUN-FU LAI  
CHIH-KANG CHIANG  
JENQ-WEN HUANG  
Huang, Sheng-Jen
DOI
10.1111/nep.12401
URI
http://europepmc.org/abstract/med/25597434
http://scholars.lib.ntu.edu.tw/handle/123456789/393802
Abstract
Aim Despite the perceived importance of frailty, few studies focus on its impact on rural patients undergoing chronic dialysis. Comparison of different self-report questionnaires in assessing frailty among these patients has not been attempted before. Methods A prospectively enrolled chronic dialysis cohort from a rural centre was recruited for analysis. Six types of self-report questionnaires were administered to these patients. Clinical and dialysis-related laboratory parameters were collected. Correlation analyses between questionnaire results and dialysis complications were performed, and variables demonstrating significant correlations were entered into multivariate regression models to determine their independent associations. Results Six types of questionnaire (Strawbridge questionnaire, Edmonton Frail Scale, simple FRAIL scale, Groningen Frail Indicator, G8 questionnaire, and Tilburg Frail Indicator) were provided to rural patients undergoing chronic dialysis. Scores from each questionnaire showed significant association with each other, except the G8 questionnaire. Scores from the simple FRAIL scale correlated significantly with age (P = 0.02), female gender (P = 0.03), higher Liu's comorbidity index (P = 0.02), lower serum albumin (P = 0.03) and creatinine levels (P < 0.01), and higher ferritin levels (P = 0.02). The other five questionnaires did not show consistently significant relationships with important dialysis-related complications. Multivariate linear regression analysis identified an independently negative association between serum albumin and the simple FRAIL scale results (P = 0.01). Conclusion This is the first study establishing the utility of different self-report questionnaires for assessing frailty in chronic dialysis patients. The simple FRAIL scale scores might demonstrate a closer relationship with dialysis-related complications. Summary at a Glance The simple FRAIL scale scores introduced in this manuscript might demonstrate a closer relationship with dialysis-related complications. This is the first study establishing the utility of different self-report questionnaires for assessing frailty in chronic dialysis patients. ? 2015 Asian Pacific Society of Nephrology.
SDGs

[SDGs]SDG3

Other Subjects
creatinine; ferritin; serum albumin; abnormal laboratory result; abnormal substrate concentration in blood; age; aged; aging; anemia; Article; clinical article; comorbidity; comparative study; creatinine blood level; dialysis; Edmonton Frail Scale; female; ferritin blood level; G8 questionnaire; gender; Groningen Frail Indicator; human; inflammation; linear regression analysis; male; malnutrition; priority journal; prospective study; questionnaire; rating scale; rural population; screening; self report; simple FRAIL scale; Strawbridge questionnaire; Tilburg Frail Indicator; adverse effects; cohort analysis; complication; frail elderly; geriatric assessment; health status indicator; Kidney Failure, Chronic; middle aged; renal replacement therapy; rural health care; sensitivity and specificity; socioeconomics; very elderly; Aged; Aged, 80 and over; Cohort Studies; Female; Frail Elderly; Geriatric Assessment; Health Status Indicators; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Rural Health Services; Self Report; Sensitivity and Specificity; Socioeconomic Factors
Type
journal article

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