Associations between ozone and preterm birth in women who develop gestational diabetes
Journal
American Journal of Epidemiology
Journal Volume
181
Journal Issue
4
Pages
280-287
Date Issued
2015
Author(s)
Abstract
Prenatal exposure to ambient air pollutants might cause adverse birth outcomes; however, there have been few studies in which the association between air pollution and preterm birth was examined after stratifying by pregnancy complications.We conducted a population-based case-control study of 1,510,064 singleton births from the Taiwanese birth registry during 2001-2007. Of the total of 1,510,064 births, we designated all 86,224 preterm births as the case group and then randomly selected an additional 344,896 from the remaining births (equivalent to 4 full-term births for every 1 preterm birth) as the control sample.We used an inverse distance weighting approach to calculate an average exposure parameter for air pollutants. The adjusted odds ratio for preterm birth per 10-ppb increase in ozonewas 1.12(95%confidence interval: 1.01, 1.23) forwomenwithgestational diabetes mellituswhowereexposed in the third trimester and 1.02 (95% confidence interval: 1.01, 1.03) for women without gestational diabetes (P for interaction <0.001). These findings suggest that exposure to ozone in pregnancy is associated with an increased risk of preterm birth, particularly for women who have gestational diabetes mellitus. ? The Author 2015.
Subjects
Air pollution; Ozone; Pregnancy complications; Preterm birth
SDGs
Other Subjects
carbon monoxide; nitrogen dioxide; ozone; sulfur dioxide; ozone; particulate matter; photochemical smog; ambient air; atmospheric pollution; diabetes; nature-society relations; ozone; pregnancy; adult; air pollutant; air pollution; Article; concentration (parameters); conception; controlled study; disease association; female; human; infant; major clinical study; male; particulate matter; population based case control study; pregnancy diabetes mellitus; pregnant woman; premature labor; prenatal exposure; second trimester pregnancy; Taiwanese; term birth; third trimester pregnancy; adverse effects; analysis; case control study; chemically induced; Diabetes, Gestational; environmental exposure; first trimester pregnancy; newborn; photochemical smog; poverty; pregnancy; pregnancy outcome; Premature Birth; risk assessment; risk factor; Taiwan; Taiwan; Adult; Air Pollution; Case-Control Studies; Diabetes, Gestational; Female; Humans; Infant, Newborn; Male; Maternal Exposure; Oxidants, Photochemical; Ozone; Particulate Matter; Poverty; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Premature Birth; Risk Assessment; Risk Factors; Taiwan
Type
journal article