https://scholars.lib.ntu.edu.tw/handle/123456789/396803
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Chen, P.-C. | en_US |
dc.contributor.author | Chang, Y.-L. | en_US |
dc.contributor.author | YU-LING CHANG | zz |
dc.creator | Chen, P.-C.;Chang, Y.-L. | - |
dc.date.accessioned | 2018-09-10T15:33:37Z | - |
dc.date.available | 2018-09-10T15:33:37Z | - |
dc.date.issued | 2016 | - |
dc.identifier.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-84961990787&partnerID=MN8TOARS | - |
dc.identifier.uri | http://scholars.lib.ntu.edu.tw/handle/123456789/396803 | - |
dc.description.abstract | This study investigated associative recognition memory by using unique features of the Chinese language and the underlying neuroanatomical correlates. The study participants were 22 Chinese speakers with mild cognitive impairment (MCI) and 25 cognitively normal (CN) Chinese speakers. The results revealed that the MCI group demonstrated impaired associative memory performance, despite exhibiting item memory performance comparable with that of the CN group, and that associative memory performance in older adults was associated with gray matter integrity in the medial temporal regions as well as executive function. An abnormal elevation was also observed in false-positive errors related to features unique to Chinese characters, namely orthographical errors, in addition to rearranged and semantic errors in the MCI group relative to the CN group, and the three error subtypes were differentially associated with gray matter integrity in the hippocampus or lateral prefrontal regions. Overall, these results demonstrate the value of evaluating associative memory in people with prodromal Alzheimer's disease (AD), and further elucidate the underlying neural substrates related to associative recognition memory in older adults. ? 2016 Elsevier Ltd. | - |
dc.language | en | en |
dc.relation.ispartof | Neuropsychologia | en_US |
dc.source | AH-Scopus to ORCID | - |
dc.subject | Alzheimer's disease; Associative memory; Gray matter; Magnetic resonance imaging; Mild cognitive impairment; Neuropsychology | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | aged; analytical error; Article; associative memory; Boston naming test; Chinese; clinical article; controlled study; correlation analysis; digit symbol substitution test; executive function; female; gray matter; hippocampus; human; language processing; male; medial temporal lobe; memory disorder; mild cognitive impairment; neuroanatomy; prefrontal cortex; prodromal symptom; recognition; semantics; Stroop test; Wechsler adult intelligence scale; Wechsler memory scale; Wisconsin Card Sorting Test; analysis of variance; brain; case control study; cognitive defect; complication; diagnostic imaging; image processing; learning; Memory Disorders; neuropsychological test; nuclear magnetic resonance imaging; physiology; very elderly; Aged; Aged, 80 and over; Analysis of Variance; Association Learning; Brain; Case-Control Studies; Cognitive Dysfunction; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Memory Disorders; Neuropsychological Tests; Verbal Learning | - |
dc.title | Associative memory and underlying brain correlates in older adults with mild cognitive impairment | - |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.neuropsychologia.2016.03.032 | - |
dc.identifier.scopus | 2-s2.0-84961990787 | - |
dc.identifier.isi | WOS:000376546400023 | - |
dc.relation.pages | 216-225 | - |
dc.relation.journalvolume | 85 | - |
item.fulltext | no fulltext | - |
item.cerifentitytype | Publications | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
crisitem.author.dept | Psychology | - |
crisitem.author.dept | Center for Artificial Intelligence and Advanced Robotics | - |
crisitem.author.orcid | 0000-0003-2851-3652 | - |
crisitem.author.parentorg | College of Science | - |
crisitem.author.parentorg | Others: University-Level Research Centers | - |
顯示於: | 心理學系 |
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