https://scholars.lib.ntu.edu.tw/handle/123456789/400155
標題: | Isoprenoids from the soft coral Sarcophyton glaucum | 作者: | CHANG-FENG DAI | 關鍵字: | Ent-sarcophyolide E; Lobocrasol; Sarcophine; Sarcophyton glaucum | 公開日期: | 2017 | 卷: | 15 | 期: | 7 | 來源出版物: | Marine Drugs | 摘要: | Five new isoprenoids, 3,4,8,16-tetra-epi-lobocrasol (1), 1,15β-epoxy-deoxysarcophine (2), 3,4-dihydro-4α,7β,8α-trihydroxy-?2-sarcophine (3), ent-sarcophyolide E (4), and 16-deacetyl-halicrasterol B (5) and ten known compounds 6-15, were characterized from the marine soft coral Sarcophyton glaucum, collected off Taitung coastline. Their structures were defined by analyzing spectra data, especially 2D NMR and electronic circular dichroism (ECD). The structure of the known compound lobocrasol (7) was revised. Cytotoxicity potential of the isolated compounds was reported, too. ?2017 by the authors. Licensee MDPI. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-85024472074&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/400155 |
DOI: | 10.3390/md15070202 | SDG/關鍵字: | 1,15beta epoxy deoxysarcophine; 16 deacetylhalicrasterol; 3,4 dihydro 4alpha hydroxy delta2 sarcophine; 3,4 dihydro 4alpha,7beta,8alpha trihydroxy delta2 sarcophine; 3,4 dihydro 4beta hydroxy delta2 sarcophine; 3,4,8,16 tetra epi lobocrasol; antineoplastic agent; ent sarcophyolide E; isoprenoid; klyflaccicembranol f; lobocrasol; loliolide; sarcoaldesterol B; sarcomilasterol; sarcophine; sarglaucsterol; srassumol A; unclassified drug; antineoplastic agent; terpene; Article; cancer cell; circular dichroism; coastal waters; concentration (parameters); coral; cytotoxicity; human; human cell; IC50; lung epithelium; MTT assay; nonhuman; nuclear magnetic resonance; Sarcophyton glaucum; Taiwan; animal; Anthozoa; chemistry; isolation and purification; nuclear magnetic resonance spectroscopy; tumor cell line; Animals; Anthozoa; Antineoplastic Agents; Cell Line, Tumor; Circular Dichroism; Humans; Magnetic Resonance Spectroscopy; Terpenes |
顯示於: | 海洋研究所 |
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