https://scholars.lib.ntu.edu.tw/handle/123456789/406497
Title: | Comprehensive structural characterization of phenolics in litchi pulp using tandem mass spectral molecular networking | Authors: | Lyu, Q. Kuo, T.-H. Sun, C. Chen, K. Hsu, C.-C. Li, X. |
Keywords: | (–)-Epicatechin (PubChem CID: 72276); GNPS; Isorhamnetin-3-O-rutinoside (PubChem CID: 5481663); Kaempferol-3-O-rutinoside (PubChem CID: 5318767); LC-ESI-MS; Litchi chinensis pulp; Phenolic compounds identification; Procyanidin B2 (PubChem CID: 122738); Quercetin-3-O-rutinoside (PubChem CID: 5280805); α-Glucosidase inhibitory activity | Issue Date: | 2019 | Journal Volume: | 282 | Start page/Pages: | 9-17 | Source: | Food Chemistry | Abstract: | Phenolic compounds are a large class of plant secondary metabolites with various health-promoting effects, and are known for their structural diversity. Therefore, high efficiency characterization of phenolic profiles is of key importance in identifying their potential bioactivity. In the present study, Global Natural Products Social (GNPS) Molecular Networking was applied to trace the phenolic compounds in plants, which allowed the characterization of 9 procyanidins and 11 flavonoid glycosides (di-, tri-, or tetra-saccharides of kaempferol, quercetin, isorhamnetin and myricetin) in litchi pulp extracts. Six compounds were reported for the first time in litchi pulp. In addition, quercetin-3-O-rutinoside-(1 → 2)-O-rhamnoside, the most abundant flavonoid glycoside in litchi pulp, was proved to have considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. ? 2019 Elsevier Ltd |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059814600&doi=10.1016%2fj.foodchem.2019.01.001&partnerID=40&md5=7bdd899ea9cc42aa4ee076e6e79992bf https://scholars.lib.ntu.edu.tw/handle/123456789/406497 |
DOI: | 10.1016/j.foodchem.2019.01.001 | SDG/Keyword: | Fruit juices; Metabolites; Phenols; Plants (botany); Sugars; GNPS; Inhibitory activity; LC-ESI-MS; Litchi chinensis; Phenolic compounds; Pubchem; Flavonoids; acarbose; alpha glucosidase; antidiabetic agent; flavonoid glycoside; isorhamnetin; isorhamnetin 3 o rutinoside; isorhamnetin 3 o rutinoside (1-2) o rhamnoside; isorhamnetin glucosylrutinoside; kaempferol; kaempferol 3 o rutinoside (1-2) o rhamnoside; keampferol rhamnosylglucosylrutinoside; myricetin; myricetin rutinoside; nicotiflorin; phenol derivative; procyanidin; procyanidin B2; quercetin; quercetin 3 o rutinoside (1-2) o rhamnoside; quercetin glucosylrutinoside; quercetin rhamnosylglucosylrutinoside; rutoside; unclassified drug; glycoside; phenol derivative; plant extract; proanthocyanidin; Article; carbon nuclear magnetic resonance; drug structure; enzyme inhibition; fruit pulp; IC50; liquid chromatography-mass spectrometry; lychee; proton nuclear magnetic resonance; structure analysis; tandem mass spectrometry; chemistry; fruit; high performance liquid chromatography; lychee; metabolism; nuclear magnetic resonance spectroscopy; Chromatography, High Pressure Liquid; Fruit; Glycosides; Litchi; Magnetic Resonance Spectroscopy; Phenols; Plant Extracts; Proanthocyanidins; Tandem Mass Spectrometry |
Appears in Collections: | 化學系 |
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