|Title:||Customizable Optical and Biofunctional Properties of a Medical Lens Based on Chemical Vapor Deposition Encapsulation of Liquids||Authors:||Wu J.-T.
|Issue Date:||2015||Journal Volume:||27||Journal Issue:||20||Start page/Pages:||7028-7033||Source:||Chemistry of Materials||Abstract:||
An innovative intraocular lens (IOL) device was fabricated based on a chemical vapor deposition encapsulation process using functionalized poly-p-xylylenes. The advanced IOL device provides noncompromised design parameters for both its optical and biological properties. As an excellent optical device, it provides a high refractive index and a tunable effective focal length that is realized by manipulating the wetting properties of the encapsulated liquids; the device also offers protection from UV radiation. As a key medical device, it exhibits excellent biocompatibility and reduced postoperative calcification through the intrinsic properties of poly-p-xylylenes. In addition, these synergic functions are provided with precise surface chemistry for location to a guided attachment or repellent properties for eye epithelial cells, which is important in preventing device-associated complications. ? 2015 American Chemical Society.
|Appears in Collections:||化學工程學系|
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