https://scholars.lib.ntu.edu.tw/handle/123456789/409856
標題: | Nanoscale Functional Polymer Coatings for Biointerface Engineering | 作者: | Chen H.-Y. Su C.-T. Tsai M.-Y. |
關鍵字: | Biointerface;Biomaterials;Paracyclophanes;Polymer;Precursors;Xylylenes | 公開日期: | 2014 | 卷: | 9.78353E+12 | 起(迄)頁: | 461-478 | 來源出版物: | Advanced Hierarchical Nanostructured Materials | 摘要: | Functionalized poly(p-xylylenes) constitute a versatile class of reactive polymers that can be prepared in a solventless process via chemical vapor deposition (CVD) polymerization. The resulting ultra-thin coatings are typically pinhole-free and can be conformally deposited onto a wide range of substrates and materials. More importantly, equipped functional groups can serve as anchoring sites to tailor biointerface properties via bioconjugation of biomolecules, which surface functions can be activated through a simple design of functionally terminated molecules, and the corresponding biological responses are efficiently and accurately manipulated. On the other hand, accessibility of multifunctional and gradient surfaces is also achieved by using these polymers to perform simultaneous manipulation of multiple types of biomolecules in a topologically and chemically confined manner. These multifunctional techniques can be complimentarily used, and provide access to precisely confined microenvironments on flat and curved geometries regardless of the underlying material used. These advanced polymers provide a technology platform that creates active and long-term control over surface properties, and may lead to improved mimicry of biological systems for sophisticated bio-functional modifications. ? 2014 Wiley-VCH Verlag GmbH & Co. All rights reserved. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/409856 | ISBN: | 9783527664948 9783527333462 |
DOI: | 10.1002/9783527664948.ch13 |
顯示於: | 化學工程學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。