https://scholars.lib.ntu.edu.tw/handle/123456789/409869
Title: | The insulation performance of reactive parylene films in implantable electronic devices | Authors: | Seymour J.P. Elkasabi Y.M. Chen H.-Y. Lahann J. Kipke D.R. |
Keywords: | Adhesion;Electrochemistry;Electronic material;Micromachining;Neural prosthesis;Parylene | Issue Date: | 2009 | Journal Volume: | 30 | Journal Issue: | 31 | Start page/Pages: | 6158-6167 | Source: | Biomaterials | Abstract: | Parylene-C (poly-chloro-p-xylylene) is an appropriate material for use in an implantable, microfabricated device. It is hydrophobic, conformally deposited, has a low dielectric constant, and superb biocompatibility. Yet for many bioelectrical applications, its poor wet adhesion may be an impassable shortcoming. This research contrasts parylene-C and poly(p-xylylene) functionalized with reactive group X (PPX-X) layers using long-term electrical soak and adhesion tests. The reactive parylene was made of complementary derivatives having aldehyde and aminomethyl side groups (PPX-CHO and PPX-CH2NH2 respectively). These functional groups have previously been shown to covalently react together after heating. Electrical testing was conducted in saline at 37 ¢XC on interdigitated electrodes with either parylene-C or reactive parylene as the metal layer interface. Results showed that reactive parylene devices maintained the highest impedance. Heat-treated PPX-X device impedance was 800% greater at 10 kHz and 70% greater at 1 Hz relative to heated parylene-C controls after 60 days. Heat treatment proved to be critical for maintaining high impedance of both parylene-C and the reactive parylene. Adhesion measurements showed improved wet metal adhesion for PPX-X, which corresponds well with its excellent high frequency performance. ? 2009 Elsevier Ltd. All rights reserved. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/409869 | ISSN: | 01429612 | DOI: | 10.1016/j.biomaterials.2009.07.061 |
Appears in Collections: | 化學工程學系 |
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