DC 欄位 | 值 | 語言 |
dc.contributor.author | 梁庚辰 | zh_TW |
dc.creator | 梁庚辰 | - |
dc.date | 2005 | zh_TW |
dc.date.accessioned | 2006-07-25T09:43:42Z | - |
dc.date.accessioned | 2018-06-28T13:26:35Z | - |
dc.date.available | 2006-07-25T09:43:42Z | - |
dc.date.available | 2018-06-28T13:26:35Z | - |
dc.date.issued | 2005 | - |
dc.identifier | 932413H002004 | zh_TW |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/9739 | - |
dc.description.abstract | The present study investigated the memory-enhancing effect of epinephrine in a
latent learning paradigm and roles of the amygdala and hippocampus in this effect.
Male albino rats were exposed to the apparatus for inhibitory avoidance training
without receiving any footshock on the first day. They were subjected to the normal
training procedure with 0.5 mA/0.5 s footshock on the second day and tested for
retention on the third day. Rats with long experience of pre-exposure had better
retention than those with short or no experience of pre-exposure. The latent learning
effect in a long pre-exposure was impaired by 4% lidocaine infused into the dorsal
hippocampus immediately after the pre-exposure experience, while lidocaine infused
into the amygdala had no such effect. Epinephrine injected systemically after a short
pre-exposure experience caused a dose- and time-dependent facilitation of the latent
memory. This effect was attenuated by infusion of 1.0 µg propranolol into the
amygdala, but the same treatment administered to the dorsal hippocampus caused no
attenuation. Intra-amygdala infusion of norepinephrine immediately after the short
pre-exposure experience also caused a dose-dependent facilitation of latent memory.
Further, intra-hippocampal infusion of lidocaine significantly attenuated enhancing
effects of epinephrine given peripherally or norepinephrine infused into the amygdala
shortly after a short pre-exposure experience. The present findings, taken together,
suggest that in an inhibitory avoidance task, peripheral epinephrine may work through
activating the amygdaloid noradrenergic functions in modulating latent learning of
contextual information relying on the dorsal hippocampus. | en |
dc.format | application/pdf | zh_TW |
dc.format.extent | 40341 bytes | - |
dc.format.mimetype | application/pdf | - |
dc.language | zh-TW | zh_TW |
dc.language.iso | zh_TW | - |
dc.publisher | 臺北市:國立臺灣大學心理學系暨研究所 | zh_TW |
dc.rights | 國立臺灣大學心理學系暨研究所 | zh_TW |
dc.subject | epinephrine | en |
dc.subject | norepinephrine | en |
dc.subject | β-adrenergic receptors | en |
dc.subject | latent learning | en |
dc.subject | contextual memory | en |
dc.title | 不同記憶系統互動之行為與神經機制的探索(2/3) | zh_TW |
dc.type | report | en |
dc.identifier.uri.fulltext | http://ntur.lib.ntu.edu.tw/bitstream/246246/9739/1/932413H002004.pdf | - |
dc.coverage | 計畫年度:93;起迄日期:2004-08-01/2005-07-31 | zh_TW |
item.openairecristype | http://purl.org/coar/resource_type/c_93fc | - |
item.openairetype | report | - |
item.languageiso639-1 | zh_TW | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.fulltext | with fulltext | - |
crisitem.author.dept | Psychology | - |
crisitem.author.dept | Center for Artificial Intelligence and Advanced Robotics | - |
crisitem.author.orcid | 0000-0002-3292-6882 | - |
crisitem.author.parentorg | College of Science | - |
crisitem.author.parentorg | Others: University-Level Research Centers | - |
顯示於: | 心理學系
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