正常老年人與額葉、顓葉及其鄰近構造病變患者之摘要性記憶功能(1/2)

Abstract

本計畫第二年的目的在於檢視正常成年人、輕微認知功能障礙患者、以及阿茲海默型失智症患者的語言與圖片摘要性記憶功能。鑑於輕微認知功能障礙的診斷準則以及阿茲海默型失智症患者的合作性問題，我們完成了70%的目標。前置性研究的結果似乎部分與國外文獻的發現相符，尤其是以校正後真實與錯誤再認分數 表現為指標的圖片摘要性記憶。我們進一步檢視三組不同運動障礙嚴重度的小樣本自發性巴金森病患，結果也顯示巴金森病患在圖片摘要性記憶表現上，有較多的錯誤記憶傾向，而這個結果與先前語言摘要性記憶作業的發現，似乎並不完全一致。由於我們受到樣本大小的限制，因此未來需要更大的樣本進一步檢視。

The aims of our 2nd year project are to examine verbal and picture gist memory function in normal aging subjects, and patients with MCI and Dementia of AD type. Because of problems of diagnostic criteria for MCI, and of DAT patients’ cooperativeness, we did accomplish 70% of these goals. The preliminary results seemed to be partially compatible with findings in the western literature, particularly the aspect of the picture gist memory, in terms of performance score indices of corrected true recognition and false recognition. We further examined three small samples of patients with idiopathic Parkinson’s disease (PD) in terms of the severity of motor disability. The results also revealed that patients with PD tended to have more false memory on the picture gist memory while there did not seemed fully consistent with the previous findings on the verbal gist memory task. Since our limited sample size, further investigation on a large scale is thus necessary.