https://scholars.lib.ntu.edu.tw/handle/123456789/412796
Title: | Causal relationships between adiposity and childhood asthma: bi-directional Mendelian Randomization analysis | Authors: | Chen, Yang-Ching Fan, Hsien-Yu Huang, Yen-Tsung Huang, Shih-Yi Liou, Tsan-Hon YUNG-LING LEE 李永凌 |
Issue Date: | 2019 | Publisher: | NATURE PUBLISHING GROUP | Journal Volume: | 43 | Journal Issue: | 1 | Start page/Pages: | 73-81 | Source: | International journal of obesity (2005) | Abstract: | Obesity and asthma are common chronic diseases and have been reported to be mutually causative. We investigated the causal direction of the relationship between adiposity and asthma using genetic markers as instrumental variables (IVs) in bi-directional Mendelian randomization (MR) analysis. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/412796 | ISSN: | 0307-0565 | DOI: | https://api.elsevier.com/content/abstract/scopus_id/85050299479 10.1038/s41366-018-0160-8 |
SDG/Keyword: | allele; allergic asthma; Article; asthma; body fat; body mass; child; childhood obesity; fat free mass; female; gene frequency; genetic variability; genome-wide association study; genotype; human; major clinical study; male; Mendelian randomization analysis; pleiotropy; priority journal; school child; single nucleotide polymorphism; skinfold; waist hip ratio; asthma; childhood obesity; complication; genetics; Mendelian randomization analysis; obesity; odds ratio; Taiwan; Adiposity; Alleles; Asthma; Body Mass Index; Child; Female; Genome-Wide Association Study; Humans; Male; Mendelian Randomization Analysis; Odds Ratio; Pediatric Obesity; Polymorphism, Single Nucleotide; Taiwan |
Appears in Collections: | 流行病學與預防醫學研究所 |
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