https://scholars.lib.ntu.edu.tw/handle/123456789/412796
標題: | Causal relationships between adiposity and childhood asthma: bi-directional Mendelian Randomization analysis | 作者: | Chen, Yang-Ching Fan, Hsien-Yu Huang, Yen-Tsung Huang, Shih-Yi Liou, Tsan-Hon YUNG-LING LEE 李永凌 |
公開日期: | 2019 | 出版社: | NATURE PUBLISHING GROUP | 卷: | 43 | 期: | 1 | 起(迄)頁: | 73-81 | 來源出版物: | International journal of obesity (2005) | 摘要: | Obesity and asthma are common chronic diseases and have been reported to be mutually causative. We investigated the causal direction of the relationship between adiposity and asthma using genetic markers as instrumental variables (IVs) in bi-directional Mendelian randomization (MR) analysis. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/412796 | ISSN: | 0307-0565 | DOI: | https://api.elsevier.com/content/abstract/scopus_id/85050299479 10.1038/s41366-018-0160-8 |
SDG/關鍵字: | allele; allergic asthma; Article; asthma; body fat; body mass; child; childhood obesity; fat free mass; female; gene frequency; genetic variability; genome-wide association study; genotype; human; major clinical study; male; Mendelian randomization analysis; pleiotropy; priority journal; school child; single nucleotide polymorphism; skinfold; waist hip ratio; asthma; childhood obesity; complication; genetics; Mendelian randomization analysis; obesity; odds ratio; Taiwan; Adiposity; Alleles; Asthma; Body Mass Index; Child; Female; Genome-Wide Association Study; Humans; Male; Mendelian Randomization Analysis; Odds Ratio; Pediatric Obesity; Polymorphism, Single Nucleotide; Taiwan |
顯示於: | 流行病學與預防醫學研究所 |
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