DC 欄位 | 值 | 語言 |
dc.contributor.author | Hu L.-C. | en_US |
dc.contributor.author | Yen W.-H. | en_US |
dc.contributor.author | Su J.-H. | en_US |
dc.contributor.author | Chiang M.Y.-N. | en_US |
dc.contributor.author | Wen Z.-H. | en_US |
dc.contributor.author | Chen W.-F. | en_US |
dc.contributor.author | Lu T.-J. | en_US |
dc.contributor.author | Chang Y.-W. | en_US |
dc.contributor.author | Chen Y.-H. | en_US |
dc.contributor.author | Wang W.-H. | en_US |
dc.contributor.author | Wu Y.-C. | en_US |
dc.contributor.author | Sung P.-J. | en_US |
dc.creator | Sung P.-J.;Wu Y.-C.;Wang W.-H.;Chen Y.-H.;Chang Y.-W.;Lu T.-J.;Chen W.-F.;Wen Z.-H.;Chiang M.Y.-N.;Su J.-H.;Yen W.-H.;Hu L.-C. | - |
dc.date.accessioned | 2019-07-16T08:48:51Z | - |
dc.date.available | 2019-07-16T08:48:51Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 16603397 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/414036 | - |
dc.description.abstract | A new norcembranoidal diterpene, 1-epi-sinulanorcembranolide A (1), and a new cembranoidal diterpene, flexibilin D (2), were isolated from the soft corals, Sinularia gaweli and Sinularia flexibilis, respectively. The structures of new metabolites 1 and 2 were elucidated by spectroscopic methods, and compound 2 was found to significantly inhibit the accumulation of the pro-inflammatory iNOS and COX-2 proteins of the lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. In addition, S. flexibilis yielded a known cembrane, 5-dehydrosinulariolide (3); the structure, including its absolute stereochemistry, was further confirmed by single-crystal X-ray diffraction analysis. ? 2013 by the authors; licensee MDPI. | en_US |
dc.language | English | - |
dc.relation.ispartof | Marine Drugs | en_US |
dc.subject | Anti-inflammatory activity | en_US |
dc.subject | Cembrane | en_US |
dc.subject | Norcembrane | en_US |
dc.subject | Sinularia flexibilis | en_US |
dc.subject | Sinularia gaweli | en_US |
dc.subject | X-ray | en_US |
dc.title | Cembrane derivatives from the soft corals, Sinularia gaweli and Sinularia flexibilis | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.3390/md11062154 | - |
dc.identifier.doi | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879497299&doi=10.3390%2fmd11062154&partnerID=40&md5=c6b63dd1b4fd71a4618a36f753ff22ab | - |
dc.identifier.scopus | 2-s2.0-84879497299 | - |
dc.identifier.url | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879497299&doi=10.3390%2fmd11062154&partnerID=40&md5=c6b63dd1b4fd71a4618a36f753ff22ab | - |
dc.relation.pages | 2154-2167 | en_US |
dc.relation.journalvolume | 11 | en_US |
dc.relation.journalissue | 6 | en_US |
item.fulltext | with fulltext | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Food Science and Technology | - |
crisitem.author.orcid | 0000-0002-3956-8272 | - |
crisitem.author.parentorg | College of Bioresources and Agriculture | - |
顯示於: | 食品科技研究所
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