https://scholars.lib.ntu.edu.tw/handle/123456789/416916
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Ho, Tsung-Chuan | en_US |
dc.contributor.author | Tsai, Shawn H | en_US |
dc.contributor.author | Yeh, Shu-I | en_US |
dc.contributor.author | SHOW-LI CHEN | en_US |
dc.contributor.author | Tung, Kwang-Yi | en_US |
dc.contributor.author | Chien, Hsin-Yu | en_US |
dc.contributor.author | Lu, Yung-Chang | en_US |
dc.contributor.author | Huang, Chang-Hung | en_US |
dc.contributor.author | Tsao, Yeou-Ping | en_US |
dc.creator | Ho, Tsung-Chuan;Tsai, Shawn H;Yeh, Shu-I;Show-Li Chen;Tung, Kwang-Yi;Chien, Hsin-Yu;Lu, Yung-Chang;Huang, Chang-Hung;Tsao, Yeou-Ping | - |
dc.date.accessioned | 2019-08-30T03:16:19Z | - |
dc.date.available | 2019-08-30T03:16:19Z | - |
dc.date.issued | 2019-01-03 | - |
dc.identifier.issn | 1757-6512 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/416916 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059502619&doi=10.1186%2fs13287-018-1110-z&partnerID=40&md5=8b1eaf9c55bdd85da7b0e8e9fcd84c15 | - |
dc.description.abstract | Tendon stem/progenitor cells (TSPC) exhibit a low proliferative response to heal tendon injury, leading to limited regeneration outcomes. Exogenous growth factors that activate TSPC proliferation have emerged as a promising approach for treatment. Here, we evaluated the pigment epithelial-derived factor (PEDF)-derived short peptide (PSP; 29-mer) for treating acute tendon injury and to determine the timing and anatomical features of CD146- and necleostemin-positive TSPC in the tendon healing process. | en_US |
dc.language.iso | en | en_US |
dc.publisher | BMC | en_US |
dc.relation.ispartof | Stem cell research & therapy | en_US |
dc.subject | PEDF; Peptide; Signaling; Tendon stem/progenitor cell | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | alginic acid; broxuridine; CD146 antigen; cell protein; collagen type 1; collagen type 3; growth factor; mitogen activated protein kinase 1; nestin; nucleostemin; octamer transcription factor 4; pigment epithelium derived factor derived short peptide; STAT3 protein; unclassified drug; eye protein; nerve growth factor; peptide; pigment epithelium-derived factor; serine proteinase inhibitor; achilles tendon rupture; adult; animal cell; animal experiment; animal model; animal tissue; Article; biomechanics; cell differentiation; cell infiltration; cell proliferation; cell stimulation; cellular distribution; clonogenesis; collagen fiber; colony formation; controlled study; drug efficacy; healing; immunohistochemistry; male; mitogenesis; New Zealand White (rabbit); nonhuman; priority journal; protein analysis; protein expression; protein phosphorylation; rat; stem cell; stem cell expansion; stem cell niche; sustained drug release; tendon healing; tendon stem cell; tenocyte; tensile strength; tissue regeneration; Western blotting; wound healing; achilles tendon; animal; cytology; genetics; human; Leporidae; metabolism; pathophysiology; regeneration; stem cell; tendon injury; Achilles Tendon; Animals; Eye Proteins; Humans; Nerve Growth Factors; Peptides; Rabbits; Rats; Regeneration; Serpins; Stem Cells; Tendon Injuries | - |
dc.title | PEDF-derived peptide promotes tendon regeneration through its mitogenic effect on tendon stem/progenitor cells | en_US |
dc.type | journal article | en |
dc.identifier.doi | https://api.elsevier.com/content/abstract/scopus_id/85059502619 | - |
dc.identifier.doi | 10.1186/s13287-018-1110-z | - |
dc.identifier.pmid | 30606221 | - |
dc.identifier.scopus | 2-s2.0-85059502619 | - |
dc.identifier.isi | WOS:000454902400002 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85059502619 | - |
dc.relation.journalvolume | 10 | en_US |
dc.relation.journalissue | 1 | en_US |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Microbiology | - |
crisitem.author.orcid | 0000-0002-6588-8632 | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 微生物學科所 |
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