|Title:||Polystyrene:β-Cyclodextrin Inclusion Complex-Supported Y<inf>2</inf>O<inf>3</inf>-Based Electrochemical Sensor: Effective and Simultaneous Determination of 4-Aminoantipyrine and Acyclovir Drugs||Authors:||Chen, Shen Ming
|Issue Date:||16-May-2019||Journal Volume:||123||Journal Issue:||19||Source:||Journal of Physical Chemistry C||Abstract:||
© 2019 American Chemical Society. In this study, a novel polystyrene:β-cyclodextrin inclusion complex-supported yttrium oxide (Y2O3)-modified glassy carbon electrode (PS:β-CD IC/Y2O3/GCE) was developed for the simultaneous determination of selected drugs, 4-aminoantipyrine (4-AAP) and acyclovir (ACV) for the first time. The results showed that PS:β-CD IC/Y2O3/GCE exhibits well-defined oxidation peak currents with a lower positive shift in peak potential in the simultaneous determination of 4-AAP and ACV compared to the bare GCE, demonstrating the superior catalytic activity. The fabricated sensor showed the linear ranges of 0.01-655 and 0.01-918 μM with low detection limits of 0.01 and 0.02 μM for the determination of 4-AAP and ACV, respectively. Further, the as-prepared PS:β-CD IC/Y2O3/GCE has been applied to the simultaneous and individual determination of 4-AAP and ACV in human urine and commercial ACV tablet samples with satisfactory recovery (98-99.3 and 88-96.6%), thereby showing a notable potential for extensive applications in the electrochemical field.
|Appears in Collections:||政治學系|
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