|Title:||Enzyme-free electrocatalytic sensing of hydrogen peroxide using a glassy carbon electrode modified with cobalt nanoparticle-decorated tungsten carbide||Authors:||Annalakshmi, Muthaiah
Chen, Tse Wei
Chen, Shen Ming
|Keywords:||Electrochemical sensor | Metal carbides | Metal nanoparticle | Non-enzymatic | Reactive oxygen species (ROS)||Issue Date:||1-Apr-2019||Journal Volume:||186||Journal Issue:||4||Source:||Microchimica Acta||Abstract:||
© 2019, Springer-Verlag GmbH Austria, part of Springer Nature. An efficient non-enzymatic electrochemical sensor for hydrogen peroxide (H 2 O 2 ) was constructed by modifying a glassy carbon electrode (GCE) with a nanocomposite prepared from cobalt nanoparticle (CoNP) and tungsten carbide (WC). The nanocomposite was prepared at low temperature through a simple technique. Its crystal structure, surface morphology and elemental composition were investigated via X-ray diffraction, transmission electron microscopy and X-ray photoelectron spectroscopy. The results showed the composite to be uniformly distributed and that the CoNP are well attached to the surface of the flake-like WC. Electrochemical studies show that the modified GCE has an improved electrocatalytic activity toward the reduction of H 2 O 2 . H 2 O 2 can be selectively detected, best at a working voltage of −0.4 V (vs. Ag/AgCl), with a 6.3 nM detection limit over the wide linear range from 50 nM to 1.0 mM. This surpasses previously reported non-enzymatic H 2 O 2 sensors. The sensor was successfully applied to the determination of H 2 O 2 in contact lens solutions and in spiked serum samples. [Figure not available: see fulltext.].
|Appears in Collections:||政治學系|
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