|Title:||Electrochemical detection of norepinephrine using sponge-like Co<inf>3</inf>O<inf>4</inf> modified screen printed carbon electrode||Authors:||Chen, Shen Ming
Weng, Wen Hui
Chen, Tse Wei
Leung, Wai Hung
Selvin, Steplin Paul
Ibrahimsa, Sharmila Lydia
Johnson, Princy Merlin
|Keywords:||Electrocatalysis | Electrochemical methods | Metal nanoparticles | Nanomaterials | Neurodegenerative diseases | Norepinephrine | Sponge like Co O 3 4||Issue Date:||1-Nov-2017||Journal Volume:||12||Journal Issue:||11||Source:||International Journal of Electrochemical Science||Abstract:||
© 2017 The Authors. Neural diseases, like Parkinson's and Alzheimer's widely increase portions of degenerative nerve disease, are related to norepinephrine (NE) concentration with proportional correlation. Quantification of NE is difficult as NE coexists with dopamine (DA), ascorbic acid (AA), and uric acid (UA), which interfere with the detection of NE in biological samples. We report the fabrication of sponge-like Co3O4 particles modified screen printed carbon electrode the for highly selective and sensitive detection of NE. Compared with recent studies, our newly developed sensor appears to have not only a wide detection range (0.1-1525 μM) but also superior detection limit (75 nM). The Co3O4 particles were prepared by simple, very cheaper and reproducible method. The effect of concentration and kinetics of electrochemical detection of NE were studied. Furthermore, the modified electrode was appreciable stability, repeatability and reproducibility. In addition, the practical feasibility of the modified sensor is demonstrated in biological samples.
|Appears in Collections:||政治學系|
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