https://scholars.lib.ntu.edu.tw/handle/123456789/425271
標題: | Tyrosinase/Chitosan/Reduced graphene oxide modified screen-printed carbon electrode for sensitive and interference-free detection of dopamine | 作者: | Liu C.-Y. Chou Y.-C. Tsai J.-H. Huang T.-M. Chen J.-Z. Yeh Y.-C. JIAN-ZHANG CHEN |
關鍵字: | Chitosan;Dopamine;Electrochemical biosensor;Reduced graphene oxide;Screen printing;Tyrosinase | 公開日期: | 2019 | 卷: | 9 | 期: | 4 | 來源出版物: | Applied Sciences (Switzerland) | 摘要: | Tyrosinase, chitosan, and reduced graphene oxide (rGO) are sequentially used to modify a screen-printed carbon electrode (SPCE) for the detection of dopamine (DA), without interference from uric acid (UA) or ascorbic acid (AA). The use of tyrosinase significantly improves the detection's specificity. Cyclic voltammetry (CV) measurements demonstrate the high sensitivity and selectivity of the proposed electrochemical sensors, with detection limits of 22 nM and broad linear ranges of 0.4-8 £gM and 40-500 £gM. The fabricated tyrosinase/chitosan/rGO/SPCE electrodes achieve satisfactory results when applied to human urine samples, thereby demonstrating their feasibility for analyzing DA in physiological samples. ? 2019 by the authors. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/425271 | ISSN: | 20763417 | DOI: | 10.3390/app9040622 https://www2.scopus.com/inward/record.uri?eid=2-s2.0-85061522533&doi=10.3390%2fapp9040622&partnerID=40&md5=4a9e930af16e3c0eb7b1741a2b089dbf |
顯示於: | 應用力學研究所 |
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applsci-09-00622.pdf | 2.83 MB | Adobe PDF | 檢視/開啟 |
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