https://scholars.lib.ntu.edu.tw/handle/123456789/426550
標題: | Gender Difference in Intraocular Pressure and Incidence of Metabolic Syndrome: A Community-Based Cohort Study in Matsu, Taiwan | 作者: | Raymond N. Kuo Yang, Chia-Ching Yen, Amy Ming-Fang Liu, Tzeng-Ying Lin, Ming-Wei Chen, Sam Li-Sheng |
關鍵字: | incidence; intraocular pressure; metabolic syndrome; prevalence; risk factor | 公開日期: | 2019 | 出版社: | MARY ANN LIEBERT, INC | 卷: | 17 | 期: | 6 | 起(迄)頁: | 334 | 來源出版物: | Metabolic syndrome and related disorders | 摘要: | Background: We aimed to assess the effect of intraocular pressure (IOP) on incident metabolic syndrome (MetS) using a longitudinal follow-up of screening cohort in contrast to most of previous studies addressing the association between both. Methods: The empirical data were derived from a community-based integrated screening program in Matsu during the period 2003 to 2010. A total of 1347 participants older than 30 years were enrolled in this study. With the enrollment of 1056 participants with MetS free at baseline, the cohort with IOP measurement in 2003 were followed up over time to identify incident MetS to elucidate the temporal sequence of both. Results: The statistically significant effect noted was that elevated IOP (≥15 mmHg vs. <15 mmHg) had 1.46-fold risk for developing incident MetS (adjusted relative ratio [aRR]: 1.46; 95% confidence interval [CI]: 1.08-1.99) for both sex combined, particularly in men (aRR: 1.66; 95% CI: 1.13-2.45) but not in women. The finding that elevated IOP occurred before the presence of high blood pressure was noted in both men and women, whereas men with elevated IOP may be concomitant with more individual components (severity) of MetS earlier than women with elevated IOP. Conclusions: Elevated IOP leading to the risk for incident or severe MetS was noted in men but not in women. Evidence on this temporal sequence revealed the possibility of showing signs of elevated IOP before the development of MetS, which indicates the necessity of monitoring IOP in routine health check-up for prevention of MetS-related chronic diseases. |
URI: | https://www2.scopus.com/inward/record.uri?eid=2-s2.0-85070445983&doi=10.1089%2fmet.2018.0131&partnerID=40&md5=361d21a3dd4c39d6b892447de99511cf https://scholars.lib.ntu.edu.tw/handle/123456789/426550 |
ISSN: | 1540-4196 | DOI: | 10.1089/met.2018.0131 | SDG/關鍵字: | glucose; abdominal obesity; adult; age; aged; Article; body mass; cohort analysis; disease association; disease severity; eye disease; fasting; female; follow up; glaucoma; Helicobacter infection; human; hypertension; intraocular pressure; longitudinal study; male; metabolic syndrome X; middle aged; postmenopause; priority journal; sex difference; smoking; complication; demography; incidence; intraocular hypertension; intraocular pressure; metabolic syndrome X; physiology; prevalence; risk factor; sex factor; Taiwan; very elderly; Adult; Aged; Aged, 80 and over; Cohort Studies; Female; Follow-Up Studies; Humans; Incidence; Intraocular Pressure; Longitudinal Studies; Male; Metabolic Syndrome; Middle Aged; Ocular Hypertension; Prevalence; Residence Characteristics; Risk Factors; Sex Factors; Taiwan |
顯示於: | 健康政策與管理研究所 |
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