https://scholars.lib.ntu.edu.tw/handle/123456789/429291
Title: | Microfluidic-Based Devices for studying effects of hydrostatic pressures on the T-cell migration and T-cell mediated cytotoxicity of cancer cells | Authors: | Po-Chan Wu Wen-Yu Wang Po-Ling Kuo PO-LING KUO |
Keywords: | Cancer cell; Cell migration; Coculture; Hydrostatic pressure; Microfluidic; T cell | Issue Date: | 2014 | Source: | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS) | Abstract: | T-cells play a central role in many physiological and pathological conditions such as cytotoxicity of cancer cells. An effective recruitment of T-cells in these conditions requires a prompt migration of T-cells from vascular trees to the pathological targets. However, the effects of increased fluid pressure on T-cell motility and other activities such as cytotoxicity of cancer cells have been barely addressed. In the present study, we demonstrated microfluidic-based platforms that have potential in studying the effects of hydrostatic pressure on the motility of T-cells and the effects of applying pressures on the T-cell mediated cytotoxicity of cancer cells. ? 14CBMS. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/429291 | SDG/Keyword: | Cell death; Cytology; Cytotoxicity; Diseases; Hydraulics; Hydrostatic pressure; Microfluidics; T-cells; Applying pressure; Cancer cells; Cell migration; Coculture; Fluid pressures; Microfluidic-based; Pathological conditions; Vascular trees; Cells |
Appears in Collections: | 電機工程學系 |
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