Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Medicine / 醫學院
  3. School of Medicine / 醫學系
  4. Outcome in children bridged and nonbridged to cardiac transplantation
 
  • Details

Outcome in children bridged and nonbridged to cardiac transplantation

Journal
Transplantation Proceedings
Journal Volume
42
Journal Issue
3
Pages
916-919
Date Issued
2010
Author(s)
Lin M.H.
NAI-KUAN CHOU  
YIH-SHARNG CHEN  
NAI-HSIN CHI  
Ko W.J.
HSI-YU YU  
SHU-CHIEN HUANG  
Wu N.T.
JOU-KOU WANG  
MEI-HWAN WU  
SHOEI-SHEN WANG  
DOI
10.1016/j.transproceed.2010.02.052
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-77955476414&doi=10.1016%2fj.transproceed.2010.02.052&partnerID=40&md5=6a973f5f791507e59bc2f6854a660737
https://scholars.lib.ntu.edu.tw/handle/123456789/434078
Abstract
Background Heart transplantation (HTx) in children with end-stage heart disease has become an accepted treatment option. Objective To evaluate our results of pediatric cardiac transplantation with vs without bridge methods. Patients and Methods The study included 31 patients (34 transplantations) younger than 18 years who underwent orthotopic HTx between March 1995 and December 2008. Ten patients were girls, and 21 were boys. Preoperative diagnoses included cardiomyopathy (n = 20), congenital heart disease (n = 7), hypertrophic cardiomyopathy (n = 2), restrictive cardiomyopathy (n = 1), and ischemic cardiomyopathy (n = 1). Mean (SD) ischemia time was 185 (72) minutes. Thirty-day mortality was 6%, and was due to primary graft failure (n = 2). Overall follow-up was 4.36 (3.93) years. Eleven patients underwent bridge techniques before HTx, and 11 patients required perioperative extracorporeal membrane oxygenation or ventricular assist device support. Results In the group that received extracorporeal membrane oxygenation, 8 patients (73%) were successfully weaned and discharged with excellent functional class. There were no differences in operative mortality, functional class, survival, rejection, and infection rates between the bridged and nonbridged groups. Overall actuarial 1- and 5-year survival rates were 93% and 83%, respectively. All survivors had good functional class. Conclusion Our findings demonstrate satisfactory medium-term outcome of HTx in selected pediatric patients with end-stage heart disease. Using bridge methods in children at high risk can increase the opportunity to receive a donor heart. These bridge methods achieve similar postoperative outcomes. ? 2010 Elsevier Inc.
SDGs

[SDGs]SDG3

Other Subjects
immunosuppressive agent; adolescent; article; child; congenital heart malformation; extracorporeal oxygenation; female; follow up; heart assist device; heart transplantation; human; hypertrophic cardiomyopathy; immunology; male; mortality; physiology; restrictive cardiomyopathy; retrospective study; survival rate; treatment outcome; Adolescent; Cardiomyopathy, Hypertrophic; Cardiomyopathy, Restrictive; Child; Extracorporeal Membrane Oxygenation; Female; Follow-Up Studies; Heart Defects, Congenital; Heart Transplantation; Heart-Assist Devices; Humans; Immunosuppressive Agents; Male; Retrospective Studies; Survival Rate; Treatment Outcome
Type
conference paper

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science