https://scholars.lib.ntu.edu.tw/handle/123456789/434084
Title: | Comparing the survival between extracorporeal rescue and conventional resuscitation in adult in-hospital cardiac arrests: Propensity analysis of three-year data | Authors: | JOU-WEI LIN MING-JIUH WANG HSI-YU YU CHIH-HSIEN WANG WEI-TIEN CHANG JIH-SHUIN JERNG SHU-CHIEN HUANG NAI-KUAN CHOU NAI-HSIN CHI Ko W.-J. Wang Y.-C. SHOEI-SHEN WANG HWANG, JUEY-JEN Lin F.-Y. YIH-SHARNG CHEN |
Issue Date: | 2010 | Journal Volume: | 81 | Journal Issue: | 7 | Start page/Pages: | 796-803 | Source: | Resuscitation | Abstract: | Aim: Extracorporeal cardiopulmonary resuscitation (ECPR) has been shown to have survival benefit over conventional CPR (CCPR) in patients with in-hospital cardiac arrest of cardiac origin. We compared the survival of patients who had return of spontaneous beating (ROSB) after ECPR with the survival of those who had return of spontaneous circulation (ROSC) after conventional CPR. Methods: Propensity score-matched cohort of adults with in-hospital prolonged CPR (>10. min) of cardiac origin in a university-affiliated tertiary extracorporeal resuscitation center were included in this study. Fifty-nine patients with ROSB after ECPR and 63 patients with sustained ROSC by CCPR were analyzed. Main outcome measures were survival at hospital discharge, 30 days, 6 months, and one year, and neurological outcome. Results: There was no statistical difference in survival to discharge (29.1% of ECPR responders vs. 22.2% of CCPR responders, p=0.394) and neurological outcome at discharge and one year later. In the propensity score-matched groups, 9 out of 27 ECPR patients survived to one month (33.3%) and 7 out of 27 CCPR patients survived (25.9%). Survival analysis showed no survival difference (HR: 0.856, p=0.634, 95% CI: 0.453-1.620) between the groups, either at 30 days or at the end of one year (HR: 0.602, p=0.093, 95% CI: 0.333-1.088). Conclusions: This study failed to demonstrate a survival difference between patients who had ROSB after institution of ECMO and those who had ROSC after conventional CPR. Further studies evaluating the role of ECMO in conventional CPR rescued patients are warranted. ? 2010 Elsevier Ireland Ltd. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953726760&doi=10.1016%2fj.resuscitation.2010.03.002&partnerID=40&md5=28e216f145abe2f668687d2920263ed7 https://scholars.lib.ntu.edu.tw/handle/123456789/434084 |
ISSN: | 0300-9572 | DOI: | 10.1016/j.resuscitation.2010.03.002 | SDG/Keyword: | adult; aged; article; breathing; controlled study; extracorporeal oxygenation; female; heart arrest; hospital care; hospital discharge; human; intermethod comparison; major clinical study; male; outcome assessment; priority journal; resuscitation; survival rate; adolescent; cause of death; cohort analysis; comparative study; confidence interval; extracorporeal oxygenation; heart arrest; Kaplan Meier method; middle aged; mortality; probability; procedures; prospective study; resuscitation; risk assessment; statistical model; survival; trends; university hospital; young adult; Academic Medical Centers; Adolescent; Adult; Aged; Cardiopulmonary Resuscitation; Cause of Death; Cohort Studies; Confidence Intervals; Extracorporeal Membrane Oxygenation; Female; Heart Arrest; Hospital Mortality; Humans; Kaplan-Meiers Estimate; Logistic Models; Male; Middle Aged; Probability; Prospective Studies; Risk Assessment; Survival Analysis; Young Adult; Academic Medical Centers; Adolescent; Adult; Aged; Cardiopulmonary Resuscitation; Cause of Death; Cohort Studies; Confidence Intervals; Extracorporeal Membrane Oxygenation; Female; Heart Arrest; Hospital Mortality; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Probability; Prospective Studies; Risk Assessment; Survival Analysis; Young Adult |
Appears in Collections: | 醫學系 |
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