Systemic contact dermatitis from valacyclovir - A case report and review of the literature
Journal
Dermatologica Sinica
Journal Volume
25
Journal Issue
1
Pages
24-29
Date Issued
2007
Author(s)
Yang C.-H.
Abstract
Acyclovir is a widely used antiviral drug. However, allergic contact dermatitis caused by acyclovir is uncommon. We herein report a 48-year-old woman, who had been diagnosed as having adenocarcinoma of the upper lobe of the right lung, developed systemic contact dermatitis sensitized by topical acyclovir therapy first, and triggered by re-exposure of oral valacyclovir and topical acyclovir therapy. A control study of 33 healthy volunteers patch tested with acyclovir (10% aq.) showed they were all negative to this preparation. We also reviewed the literature and discussed the methods of patch testing in diagnosing drug allergy.
Subjects
Acyclovir; Allergic contact dermatitis; Patch test; Valacyclovir
SDGs
Other Subjects
aciclovir; chloramphenicol; chlorhexidine gluconate; fluticasone; fluticasone propionate; nickel sulfate; povidone iodine; valaciclovir; adult; anamnesis; article; case report; contact dermatitis; female; herpes zoster; human; lung adenocarcinoma; patch test; skin biopsy; skin examination
Type
journal article