https://scholars.lib.ntu.edu.tw/handle/123456789/444451
DC 欄位 | 值 | 語言 |
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dc.contributor.author | Wan M.T. | en_US |
dc.contributor.author | Fu S.Y. | en_US |
dc.contributor.author | Lo Y.P. | en_US |
dc.contributor.author | Huang T.M. | en_US |
dc.contributor.author | Cheng M.M. | en_US |
dc.contributor.author | MEEI-MEI CHEN | en_US |
dc.contributor.author | CHIN-CHENG CHOU | en_US |
dc.creator | Wan M.T.;Fu S.Y.;Lo Y.P.;Huang T.M.;Cheng M.M.;Chou C.C. | - |
dc.date.accessioned | 2020-01-03T06:13:26Z | - |
dc.date.available | 2020-01-03T06:13:26Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1364-5072 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/444451 | - |
dc.description.abstract | Aims: To investigate the distribution of staphylococcal enterotoxin genes (se) and the molecular features of community-associated methicillin-sensitive/resistant Staphylococcus aureus (CA-MSSA/MRSA) isolates in the nostrils of healthy pets and their owners. Methods and Results: A total of 114 Staph. aureus isolates were identified from 1563 nasal swab samples, and CA-MRSA accounted for 20·2% (n=23) of the total identified isolates. CA-MRSA isolates (91·3%, 21/23) harboured higher percentage of se than did CA-MSSA isolates (58·2%, 53/91) (P<0·01), and the two highest se profiles of CA-MRSA were seb-sek-seq (42·9%, 9/21) and seb-sek-seq-sep (28·6%, 6/21). Of the MSSAs, 42·8% (39/91) were resistant to at least one antimicrobial drug and 8·8% (8/91) were multidrug resistant (MDR). We identified nine staphylocoagulase (SC) types (I-VIII and X) and three multilocus sequence types (ST59-MRSA-IV/V, ST-239-MRSA-V and ST241-MRSA-V). SC VII (23·4%, 22/94), a staphylococcal food poisoning isolate found mainly in Japan, and ST-59-MRSA-IV/V (85%, 17/20), a widespread CA-MRSA clone found mainly in Taiwan, both were the most predominant types. Phylogenetic analysis together with se and molecular characteristics obtained using pulsed-field gel electrophoresis showed that high levels of antimicrobial resistance and the se-carrying clone ST59-MRSA-IV/V-SC VII were all clustered in genogroup 5. Conclusions: The CA-MRSA clone of se-carrying-MDR-ST-59-IV/V-SC VII was identified predominantly in this study, and this clone might play a significant role in staphylococcal food poisoning in community settings. Significance and Impact of the Study: To our knowledge, this is the first study focussing on enterotoxin-carrying CA-MRSA/MSSA in pets and their owners, and the results support the future warnings in animal-human bond caused by CA-staphylococci in the commonwealth and the need to take cautions worldwide. ? 2011 The Authors. Journal of Applied Microbiology ? 2011 The Society for Applied Microbiology. | - |
dc.relation.ispartof | Journal of Applied Microbiology | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | cefoxitin; chloramphenicol; clindamycin; coagulase; erythromycin; gentamicin; oxacillin; rifampicin; Staphylococcus enterotoxin; tetracycline; vancomycin; antibiotic resistance; antimicrobial activity; bacterium; canid; chromosome; domestic species; electrokinesis; felid; food poisoning; gene expression; health risk; heterogeneity; microbial community; phylogenetics; public health; relatedness; toxin; antibiotic resistance; antibiotic sensitivity; article; bacterium identification; bacterium isolate; cat; coagulase positive Staphylococcus; controlled study; dog; gene cluster; genetic heterogeneity; heterozygote; human; methicillin resistant Staphylococcus aureus; methicillin susceptible Staphylococcus aureus; molecular cloning; multidrug resistance; multilocus sequence typing; nonhuman; nose; nose smear; phylogeny; pulsed field gel electrophoresis; staphylococcal food poisoning; Animals; Anti-Infective Agents; Cats; Coagulase; DNA, Bacterial; Dogs; Electrophoresis, Gel, Pulsed-Field; Enterotoxins; Genetic Heterogeneity; Genotype; Humans; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phylogeny; Prevalence; Staphylococcus aureus; Taiwan; Japan; Taiwan; Animalia; Canis familiaris; methicillin resistant Staphylococcus aureus; Staphylococcus; Staphylococcus aureus | - |
dc.title | Heterogeneity and phylogenetic relationships of community-associated methicillin-sensitive/resistant Staphylococcus aureus isolates in healthy dogs, cats and their owners | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1111/j.1365-2672.2011.05179.x | - |
dc.identifier.scopus | 2-s2.0-83555179111 | - |
dc.identifier.url | https://www2.scopus.com/inward/record.uri?eid=2-s2.0-83555179111&doi=10.1111%2fj.1365-2672.2011.05179.x&partnerID=40&md5=21ab1dd9952ad1754618bab93a49f07d | - |
dc.relation.pages | 205-213 | - |
dc.relation.journalvolume | 112 | - |
dc.relation.journalissue | 1 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Veterinary Medicine | - |
crisitem.author.orcid | 0000-0001-6052-4701 | - |
crisitem.author.orcid | 0000-0001-7908-4312 | - |
crisitem.author.parentorg | College of Bioresources and Agriculture | - |
顯示於: | 獸醫學系 |
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