https://scholars.lib.ntu.edu.tw/handle/123456789/453959
標題: | Ultrasonographic features for differentiating follicular thyroid carcinoma and follicular adenoma | 作者: | TING-CHUN KUO MING-HSUN WU KUEN-YUAN CHEN MIN-SHU HSIEH ARGON CHEN CHIUNG-NIEN CHEN |
公開日期: | 2020 | 出版社: | Elsevier (Singapore) Pte Ltd | 卷: | 43 | 期: | 1 | 起(迄)頁: | 339-346 | 來源出版物: | Asian Journal of Surgery | 摘要: | Background: Preoperative differentiation of follicular thyroid carcinoma (FTC) from follicular adenoma (FA) remains an unsolved puzzle. Patients sometimes undergo unnecessary lobectomy for histology confirmation inevitably. Objective: In this retrospective study, we propose new gray-scale ultrasonographic (US) features that may help to differentiate FTC from FA. Method: Medical charts and US images of follicular thyroid neoplasms were collected prospectively. Gray-scale US features including conventional parameters adding tubercle-in-nodule and trabecular formation were recorded. Results: The histopathologic diagnosis was FA in 139 and FTC in 49 patients. In patients with FTC, minimally invasive follicular carcinoma (MIFC) was seen in 36 patients and widely invasive follicular carcinoma (WIFC) in 13. The incidences of calcifications (p < 0.0001), tubercle-in-nodule signs (p < 0.0001), spiculated margins (p = 0.014), and trabecular formations (p = 0.03) were significantly higher in FTC. Tubercle-in-nodule (p < 0.01) and calcification (p < 0.001) were independent factors in the differentiation of FTC in multivariate analysis (area under the curve = 0.689). Conclusions: US characteristics of tubercle-in-nodule in combination with calcification help to differentiate FTC from FA. ? 2019 |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066821231&doi=10.1016%2fj.asjsur.2019.04.016&partnerID=40&md5=24b0d31191a6fba0b20042860cfa4ed3 https://scholars.lib.ntu.edu.tw/handle/123456789/453959 |
ISSN: | 1015-9584 | DOI: | 10.1016/j.asjsur.2019.04.016 | SDG/關鍵字: | adenocarcinoma; adenoma; adolescent; adult; aged; calcinosis; child; diagnostic imaging; differential diagnosis; echography; female; human; male; middle aged; pathology; retrospective study; thyroid tumor; very elderly; young adult; Adenocarcinoma, Follicular; Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Calcinosis; Child; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Retrospective Studies; Thyroid Neoplasms; Ultrasonography; Young Adult |
顯示於: | 醫學系 |
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