Junceol A, a New Sesquiterpenoid from the Sea Pen Virgularia juncea
Resource
Journal of Natural Products 64 (9): 1241-1242
Journal
Journal of Natural Products
Journal Volume
64
Journal Issue
9
Pages
1241-1242
Date Issued
2001
Date
2001
Author(s)
Abstract
A new sesquiterpenoid, junceol A(1), as well as two known diterpenoids, sclerophytin A (2) and cladiellisin (3), have been isolated from the sea pen octocoral Virgularia juncea. The structure of metabolite 1 was determined by extensive spectral analysis. Compounds 1-3 have been shown to exhibit cytotoxicity toward P-388 cancer cells.
Other Subjects
cladiellisin; diterpenoid; junceol a; sclerophytin A; sesquiterpenoid; unclassified drug; Virgularia juncea extract; animal cell; article; cancer cell; controlled study; cytotoxicity; drug activity; drug identification; drug isolation; drug structure; mouse; nonhuman; spectroscopy; structure activity relation; structure analysis; Animals; Bridged Compounds; Chromatography, Thin Layer; Cnidaria; Drug Screening Assays, Antitumor; Furans; Inhibitory Concentration 50; Leukemia P388; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Sesquiterpenes; Spectrophotometry, Infrared; Taiwan; Tumor Cells, Cultured; Animalia; Invertebrata; Pennatulacea; Virgularia juncea
Type
journal article
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