https://scholars.lib.ntu.edu.tw/handle/123456789/45848
標題: | New Cytotoxic Xenia Diterpenoids from the Formosan Soft Coral Xenia umbellata | 作者: | Duh, Chang-Yih El-Gamal, Ali Ali H. Chiang, Chin-Ying Chu, Chih-Ju Wang, Shang-Kwei CHANG-FENG DAI |
公開日期: | 2002 | 卷: | 65 | 期: | 12 | 起(迄)頁: | 1882-1885 | 來源出版物: | Journal of Natural Products | 摘要: | Seven new cytotoxic xenicane-type diterpenoids, 9-deoxyxeniloide-E (1), 9-deoxy-7,8-epoxyxeniloide-E (2), xeniolide-G (3), 9-deoxyxenialactol-C (4), xenibecin (5), xeniolide-H (6), and xenitacin (7), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia umbellata. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-0036931607&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/297324 http://ntur.lib.ntu.edu.tw/bitstream/246246/174315/1/24.pdf |
DOI: | 10.1021/np020268z | SDG/關鍵字: | 9 deoxy 7,8 epoxyxeniloide E; 9 deoxyxenialactol C; 9 deoxyxeniloide E; dichloromethane; diterpenoid; unclassified drug; xenibecin; xeniolide G; xeniolide H; xenitacin; article; cancer cell culture; carbon nuclear magnetic resonance; controlled study; drug cytotoxicity; drug isolation; human; human cell; in vitro study; nuclear Overhauser effect; proton nuclear magnetic resonance; stereochemistry; structure activity relation; Animals; Anthozoa; Antineoplastic Agents; Chromatography, Thin Layer; Colonic Neoplasms; Diterpenes; Drug Screening Assays, Antitumor; Leukemia P388; Lung Neoplasms; Mice; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Taiwan; Tumor Cells, Cultured; Alcyonacea; Anthozoa |
顯示於: | 海洋研究所 |
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