https://scholars.lib.ntu.edu.tw/handle/123456789/45851
標題: | New Cytotoxic Constituents from the Formosan Soft Corals Clavularia viridis and Clavularia violacea | 作者: | Duh, Chang-Yih El-Gamal, Ali Ali H. Chu, Chih-Ju Wang, Shang-Kwei CHANG-FENG DAI |
公開日期: | 2002 | 卷: | 65 | 期: | 11 | 起(迄)頁: | 1535-1539 | 來源出版物: | Journal of Natural Products | 摘要: | Three new cytotoxic prostanoids, claviridenone E-G (1-3), and three new cytotoxic steroids, stoloniferone E-G (4-6), were isolated from the methylene chloride solubles of the Formosan soft coral Clavularia viridis. A cytotoxic cembranoid, claviolide (7), was isolated from the methylene chloride solubles of the Formosan soft coral Clavularia violacea. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-0036854760&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/297325 http://ntur.lib.ntu.edu.tw/bitstream/246246/174318/1/25.pdf |
DOI: | 10.1021/np0201873 | SDG/關鍵字: | cembranoid; claviolide; claviridenone e; claviridenone f; claviridenone g; dichloromethane; prostanoid; steroid; stoloniferone e; stoloniferone f; stoloniferone g; unclassified drug; antineoplastic activity; article; cancer cell culture; Clavularia violacea; clavularia viridis; coral; cytotoxicity; drug structure; in vitro study; nuclear magnetic resonance spectroscopy; structure analysis; Taiwan; Animals; Anthozoa; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Lung Neoplasms; Methylene Chloride; Mice; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Prostaglandins; Steroids; Taiwan; Tumor Cells, Cultured; Alcyonacea; Anthozoa; Clavularia; Clavularia viridis; Invertebrata |
顯示於: | 海洋研究所 |
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